University of Oklahoma College of Medicine, Oklahoma City, OK, USA.
Department of Ophthalmology, Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, 608 Stanton L Young Blvd, Oklahoma City, OK, 73104, USA.
J Med Case Rep. 2024 Jun 8;18(1):272. doi: 10.1186/s13256-024-04596-y.
To report a case of Multiple Evanescent White Dot Syndrome (MEWDS) one month after a COVID-19 infection in a female patient at an age unusual for the occurrence of this disease.
A 69-year-old Caucasian female reported the presence of floaters, photopsia, and enlarging vision loss in her left eye following the COVID-19 infection. Clinical and multimodal imaging was consistent with the MEWDS diagnosis. Fluorescein angiography examination revealed characteristic hyperfluorescent spots around the fovea in a wreath-like pattern. An extensive lab workup to rule out other autoimmune and infectious etiologies was inconclusive. Visual acuity and white dots resolved after a course of corticosteroids, which was confirmed on follow-up dilated fundus exam and multimodal imaging.
MEWDS is a rare white dot syndrome that may occur following COVID-19 infection in addition to other reported ophthalmic disorders following this infection.
报告一例女性患者在 COVID-19 感染一个月后患多发性一过性白点综合征(MEWDS),其发病年龄不常见。
一名 69 岁的白人女性在 COVID-19 感染后出现飞蚊症、闪光感和左眼视力逐渐丧失。临床和多模态影像学检查符合 MEWDS 的诊断。荧光素血管造影检查显示在一个呈环状的黄斑周围有特征性的高荧光斑点。为排除其他自身免疫和感染性病因进行了广泛的实验室检查,但结果不确定。皮质类固醇治疗后视力和白点消退,在后续的散瞳眼底检查和多模态影像学检查中得到证实。
MEWDS 是一种罕见的白班综合征,除了其他报告的 COVID-19 感染后的眼部疾病外,还可能在 COVID-19 感染后发生。