Paul Munish
Skin Laser Center, New Delhi, India.
J Cutan Aesthet Surg. 2011 Jan;4(1):23-8. doi: 10.4103/0974-2077.79183.
Autologous non-cultured basal cell-enriched epidermal cell suspension transplantation is a simple yet effective cell-based therapy for vitiligo.
This report is a retrospective analysis of 58 patients who were operated between December 2003 and August 2006 and were under follow-up for at least 2 years. Nine patients did not come for follow-up, and were excluded. At the time of transplantation all patients were having stable disease for at least 1 year. Epidermal cell suspension transplantation was done using Mulekar's method. Repigmentation was assessed and classified into excellent (>90% repigmentation), good (70-89%), fair (30-69%) and poor (<30%).
Of the 49 patients who came for follow-up, 32 (65%) had excellent (>90%) repigmentation; 9 (18%) had good (70-89%); 4 (8%) had fair (30-69%) and 4 (8%) patients had poor (<30%) repigmentation. During the follow-up, eight patients(16%) showed relapse of the disease.
Autologous noncultured basal cell-enriched epidermal cell suspension transplantation is an effective, simple and safe method.
自体非培养富含基底细胞的表皮细胞悬液移植是一种治疗白癜风的简单而有效的细胞疗法。
本报告是对2003年12月至2006年8月间接受手术且至少随访2年的58例患者的回顾性分析。9例患者未前来随访，被排除。移植时所有患者病情稳定至少1年。采用穆勒卡尔法进行表皮细胞悬液移植。对色素再生情况进行评估并分为优（色素再生>90%）、良（70 - 89%）、中（30 - 69%）和差（<30%）。
前来随访的49例患者中，32例（65%）色素再生优（>90%）；9例（18%）良（70 - 89%）；4例（8%）中（30 - 69%）；4例（8%）差（<30%）。随访期间，8例患者（16%）病情复发。
自体非培养富含基底细胞的表皮细胞悬液移植是一种有效、简单且安全的方法。
