Wauye Victor M, Njiru Evangeline, Amadi Angela K, Hagembe Mildred N, Kigen Gabriel
Department of Internal Medicine, School of Medicine College of Health Sciences, Moi University Eldoret Kenya.
Department of Internal Medicine Moi Teaching and Referral Hospital Eldoret Kenya.
Clin Case Rep. 2024 Jun 7;12(6):e9048. doi: 10.1002/ccr3.9048. eCollection 2024 Jun.
Chronic myelomonocytic leukemia, a rare case of hematological malignancy mainly affects the elderly and may present with life threatening pericardial effusion as an initial manifestation. High index of suspicion is hence key for early management.
We present a case of an 81-year-old African male who presented with progressive cough, respiratory distress and bilateral lower limb swelling, and was diagnosed with life-threatening pericardial effusion resulting from chronic myelomonocytic leukemia following complete blood count, peripheral blood film, bone marrow aspirate with trephine biopsy, and flow cytometry studies.
慢性粒单核细胞白血病是一种罕见的血液系统恶性肿瘤,主要影响老年人,可能以危及生命的心包积液作为初始表现。因此,高度怀疑指数是早期管理的关键。
我们报告一例81岁非洲男性病例,该患者出现进行性咳嗽、呼吸窘迫和双侧下肢肿胀,经全血细胞计数、外周血涂片、骨髓穿刺及活检、流式细胞术检查后,诊断为慢性粒单核细胞白血病导致的危及生命的心包积液。