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[致癌物——环境诱变/致癌物的检测方法]

[A carcinogens--methods for detecting environmental muta/carcinogens].

作者信息

Morimoto K, Koizumi A

出版信息

Gan To Kagaku Ryoho. 1985 Apr;12(4):789-97.

PMID:3885860
Abstract

The major causes of cancer in the developed countries are now thought to be environmental or man-made factors. Because most carcinogens are also mutagens, the detection and identification of muta/carcinogens to humans seem to be very important in the environmental sciences. We describe here, i) in vitro and in vivo short-term assays for muta/carcinogens in the environment, ii) possible method for monitoring human exposure to muta/carcinogens, and iii) some trials for estimating human risk for the development of cancers due to environmental mutagens.

摘要

现在认为,发达国家癌症的主要病因是环境或人为因素。由于大多数致癌物也是诱变剂,因此在环境科学中,检测和鉴定对人类有诱变/致癌作用的物质显得非常重要。我们在此描述:i)环境中诱变/致癌物质的体外和体内短期检测方法;ii)监测人类接触诱变/致癌物质的可能方法;iii)一些评估人类因环境诱变剂而患癌风险的试验。

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