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人类嗅觉通路中的嗅觉标记蛋白。

Olfactory marker protein in the human olfactory pathway.

作者信息

Nakashima T, Kimmelman C P, Snow J B

出版信息

Arch Otolaryngol. 1985 May;111(5):294-7. doi: 10.1001/archotol.1985.00800070046004.

DOI:10.1001/archotol.1985.00800070046004
PMID:3885925
Abstract

The presence of olfactory marker protein (OMP) in the olfactory tissue of rats, gerbils, and humans was demonstrated with goat antiserum to rat OMP. In control studies on rat neural tissue, OMP was found to be located in the olfactory receptor cells, nerves, and bulbs. Likewise, staining of OMP was found in the olfactory tissues of gerbils. Olfactory marker protein reactivity was also demonstrated in human olfactory receptor cells, nerves, and bulbs. The reactivity of OMP in human olfactory neurons to goat antiserum has allowed determination of the exact junction of olfactory and respiratory epithelia immunohistochemically.

摘要

用抗大鼠嗅觉标记蛋白(OMP)的山羊抗血清证实了大鼠、沙鼠和人类嗅觉组织中存在OMP。在对大鼠神经组织的对照研究中,发现OMP位于嗅觉受体细胞、神经和嗅球中。同样,在沙鼠的嗅觉组织中也发现了OMP染色。在人类嗅觉受体细胞、神经和嗅球中也证实了嗅觉标记蛋白的反应性。人嗅觉神经元中OMP对山羊抗血清的反应性使得能够通过免疫组织化学方法确定嗅觉上皮和呼吸上皮的确切交界处。

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