Greenberg R N, Bollinger M
Clin Ther. 1985;7(2):151-3.
Twenty-seven Escherichia coli test strains that were not susceptible to cephalothin were tested for susceptibility to cefazolin, cefamandole, and ceforanide. By zone-size criteria (greater than or equal to 18 mm), 67% of E coli were susceptible to cefazolin and cefamandole, and 93% were susceptible to ceforanide. By microtiter assay (MIC less than or equal to 8 micrograms/ml), 88% were susceptible to cefazolin and cefamandole, and 94% were susceptible to ceforanide. The results support susceptibility testing of E coli with specific first- or second-generation cephalosporins rather than with class agents.
对27株对头孢噻吩不敏感的大肠杆菌测试菌株进行了对头孢唑林、头孢孟多和头孢尼西的敏感性测试。根据抑菌圈大小标准(大于或等于18毫米),67%的大肠杆菌对头孢唑林和头孢孟多敏感,93%对头孢尼西敏感。通过微量滴定法(最低抑菌浓度小于或等于8微克/毫升),88%对头孢唑林和头孢孟多敏感,94%对头孢尼西敏感。结果支持用特定的第一代或第二代头孢菌素而非同类药物对大肠杆菌进行敏感性测试。