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急性窒息对子宫内胎猪影响的研究。

Studies on the effect of acute asphyxia on the fetal pig in utero.

作者信息

Randall G C

出版信息

Biol Neonate. 1979;36(1-2):63-9. doi: 10.1159/000241208.

DOI:10.1159/000241208
PMID:38863
Abstract

8 term fetal pigs (110-112 days gestation) and one 97-day fetus were asphyxiated in utero by occlusion of the umbilical cord. Mean times to last gasp and last heart beat were 5.1 and 22.4 for term and 5.4 and 30.4 min for the 97-day fetus. Cord occlusion was followed by profound bradycardia and an increase in blood pressure which was maintained until gasping ceased. Profound acidemia, hypercapnia and hyperlactacidemia developed in all animals and values following asphyxiation were comparable with those seen in stillborn piglets. Liver and cardiac glycogen levels were lower in asphyxiated fetuses than in littermates but muscle glycogen levels were similar in both groups.

摘要

8只足月胎猪(妊娠110 - 112天)和1只97天的胎儿通过阻断脐带在子宫内窒息。足月胎猪最后喘息和最后心跳的平均时间分别为5.1分钟和22.4分钟,97天胎儿的相应时间分别为5.4分钟和30.4分钟。脐带阻断后出现严重心动过缓和血压升高,这种情况一直持续到喘息停止。所有动物均出现严重酸血症、高碳酸血症和高乳酸血症,窒息后的各项指标与死产仔猪相似。窒息胎儿的肝脏和心脏糖原水平低于同窝仔猪,但两组的肌肉糖原水平相似。

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