Department of Neurology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, United States.
Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, United States.
Cereb Cortex. 2024 Jun 4;34(6). doi: 10.1093/cercor/bhae213.
Neuropsychological and neuroimaging studies provide evidence for a degree of category-related organization of conceptual knowledge in the brain. Some of this evidence indicates that body part concepts are distinctly represented from other categories; yet, the neural correlates and mechanisms underlying these dissociations are unclear. We expand on the limited prior data by measuring functional magnetic resonance imaging responses induced by body part words and performing a series of analyses investigating the cortical representation of this semantic category. Across voxel-level contrasts, pattern classification, representational similarity analysis, and vertex-wise encoding analyses, we find converging evidence that the posterior middle temporal gyrus, the supramarginal gyrus, and the ventral premotor cortex in the left hemisphere play important roles in the preferential representation of this category compared to other concrete objects.
神经心理学和神经影像学研究为大脑中概念知识的某种程度的类别相关组织提供了证据。这些证据中的一部分表明，身体部位的概念与其他类别明显不同；然而，这些区别的神经关联和机制尚不清楚。我们通过测量身体部位词汇引起的功能性磁共振成像反应，并进行一系列分析来研究这个语义类别在皮质上的表现，从而扩展了有限的先前数据。通过体素水平对比、模式分类、代表性相似性分析和顶点编码分析，我们发现一致的证据表明，左半球的后颞中回、缘上回和腹侧前运动皮层在这个类别相对于其他具体物体的优先表现中起着重要作用。
