• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

以胆囊积脓为表现的胆总管胆管癌：一例罕见病例报告

Cholangiocarcinoma of the Common Bile Duct Presenting as Empyema of the Gallbladder: A Rare Case Report.

作者信息

Khaladkar Sanjay M, Jhala Neeha A, Dhande Aryaman N, KirdatPatil Prajakta P, M Suhas

机构信息

Radiodiagnosis, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.

出版信息

Cureus. 2024 May 8;16(5):e59865. doi: 10.7759/cureus.59865. eCollection 2024 May.

DOI:10.7759/cureus.59865
PMID:38864065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11166205/
Abstract

Cholangiocarcinoma of the common bile duct (CBD) presenting as empyema of the gallbladder is a rare entity that poses a risk of septicemia, septic shock, peritonitis, and abscess formation. This case report describes an elderly female presenting with pain in the right hypochondrium, a positive Murphy's sign, and a history of regurgitation and constipation. It highlights the value of imaging in the early diagnosis of this rare presentation of underlying malignancy. The most common cause of empyema of the gallbladder is acute cholecystitis, followed by gallbladder neck obstruction by a calculus. This report discusses the important role of imaging supported by clinical history, examination, laboratory tests, and histopathological findings to diagnose this rare presentation of empyema of the gallbladder as a complication of underlying cholangiocarcinoma. Additionally, it briefly discusses the change in the management line for cholangiocarcinoma patients with complications such as gallbladder perforation and septicemia. The study concludes that the possibility of underlying bile duct malignancy cannot be overlooked in patients with similar symptoms, particularly among the elderly.

摘要

表现为胆囊积脓的胆总管胆管癌是一种罕见疾病，存在败血症、感染性休克、腹膜炎及脓肿形成的风险。本病例报告描述了一名老年女性，有右季肋部疼痛、墨菲氏征阳性，并有反流和便秘史。它强调了影像学检查在早期诊断这种罕见的潜在恶性肿瘤表现中的价值。胆囊积脓最常见的原因是急性胆囊炎，其次是结石阻塞胆囊颈部。本报告讨论了影像学检查在结合临床病史、体格检查、实验室检查及组织病理学结果以诊断这种罕见的胆囊积脓表现为潜在胆管癌并发症中的重要作用。此外，还简要讨论了胆管癌合并胆囊穿孔和败血症等并发症患者治疗方案的改变。该研究得出结论，有类似症状的患者，尤其是老年人，不能忽视潜在胆管恶性肿瘤的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/4707b25bc150/cureus-0016-00000059865-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/72d7119d3636/cureus-0016-00000059865-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/2c4c48c15f05/cureus-0016-00000059865-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/6519094c8032/cureus-0016-00000059865-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/cb2d429fc667/cureus-0016-00000059865-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/1e5beaf823f3/cureus-0016-00000059865-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/67bfbbfbb0e9/cureus-0016-00000059865-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/2b488f94d034/cureus-0016-00000059865-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/42681e91ff28/cureus-0016-00000059865-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/eb78fd4c6a6d/cureus-0016-00000059865-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/4313477bc3e6/cureus-0016-00000059865-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/4707b25bc150/cureus-0016-00000059865-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/72d7119d3636/cureus-0016-00000059865-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/2c4c48c15f05/cureus-0016-00000059865-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/6519094c8032/cureus-0016-00000059865-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/cb2d429fc667/cureus-0016-00000059865-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/1e5beaf823f3/cureus-0016-00000059865-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/67bfbbfbb0e9/cureus-0016-00000059865-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/2b488f94d034/cureus-0016-00000059865-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/42681e91ff28/cureus-0016-00000059865-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/eb78fd4c6a6d/cureus-0016-00000059865-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/4313477bc3e6/cureus-0016-00000059865-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc6/11166205/4707b25bc150/cureus-0016-00000059865-i11.jpg

相似文献

1
Cholangiocarcinoma of the Common Bile Duct Presenting as Empyema of the Gallbladder: A Rare Case Report.以胆囊积脓为表现的胆总管胆管癌：一例罕见病例报告
Cureus. 2024 May 8;16(5):e59865. doi: 10.7759/cureus.59865. eCollection 2024 May.
2
[Clinical manifestations of cholelithiasis and its complications].[胆结石及其并发症的临床表现]
Praxis (Bern 1994). 1995 May 16;84(20):590-5.
3
Palliative percutaneous transhepatic gallbladder drainage of gallbladder empyema before laparoscopic cholecystectomy.在腹腔镜胆囊切除术之前对胆囊积脓进行姑息性经皮经肝胆囊引流术。
Hepatogastroenterology. 2000 Jul-Aug;47(34):932-6.
4
Ultrasound-guided percutaneous transhepatic drainage of gallbladder followed by cholecystectomy for acute cholecystitis--10 years' experience.超声引导下经皮经肝胆囊引流术治疗急性胆囊炎后行胆囊切除术——10年经验
Kaohsiung J Med Sci. 1998 Jan;14(1):19-24.
5
A Rare Case of Trifoliate Gallbladder in an Adult Male and Its Management: A Comprehensive Case Report and Literature Review.成年男性三叶胆囊1例及其处理：病例报告与文献综述
Cureus. 2023 Oct 17;15(10):e47180. doi: 10.7759/cureus.47180. eCollection 2023 Oct.
6
Rare case report of acalculous cholecystitis: Gallbladder torsion resulting in rupture.无结石性胆囊炎罕见病例报告：胆囊扭转导致破裂。
SAGE Open Med Case Rep. 2019 Jan 11;7:2050313X18823385. doi: 10.1177/2050313X18823385. eCollection 2019.
7
Gallbladder Torsion Masking as Acalculus Cholecystitis: A Review of Two Cases Including Unsuccessful Management With Percutaneous Cholecystostomy.胆囊扭转伪装成无结石性胆囊炎：两例病例回顾，包括经皮胆囊造瘘术治疗失败
J Med Cases. 2021 Jun;12(6):223-225. doi: 10.14740/jmc3683. Epub 2021 Mar 20.
8
Management of empyema of gallbladder with percutaneous cholecysto-duodenal stenting in a case of hilar cholangiocarcinoma treated with common bile duct metallic stenting.经皮胆囊十二指肠支架置入术治疗肝门部胆管癌行胆总管金属支架置入术后并发胆囊积脓的处理
Indian J Radiol Imaging. 2011 Oct;21(4):298-300. doi: 10.4103/0971-3026.90695.
9
Acute severe cholecystitis with empyema presenting as a gallbladder mass, jaundice and Mirizzi Syndrome: A case report.以胆囊肿块、黄疸和Mirizzi综合征为表现的急性重症胆囊炎伴积脓：一例报告
Int J Surg Case Rep. 2021 Jan;78:223-227. doi: 10.1016/j.ijscr.2020.12.035. Epub 2020 Dec 16.
10
Empyema of the gallbladder: a complication in the natural history of acute cholecystitis.胆囊积脓：急性胆囊炎自然病程中的一种并发症。
Am J Surg. 1981 Mar;141(3):366-9. doi: 10.1016/0002-9610(81)90198-7.

本文引用的文献

1
NCCN Guidelines® Insights: Biliary Tract Cancers, Version 2.2023.NCCN 指南®洞察：胆道癌，第 2.2023 版。
J Natl Compr Canc Netw. 2023 Jul;21(7):694-704. doi: 10.6004/jnccn.2023.0035.
2
Main causes of death in advanced biliary tract cancer.晚期胆道癌的主要死亡原因。
Cancer Med. 2023 May;12(9):10889-10898. doi: 10.1002/cam4.5794. Epub 2023 Mar 29.
3
Gallbladder Carcinoma and Its Differential Diagnosis at MRI: What Radiologists Should Know.胆囊癌及其MRI鉴别诊断：放射科医生应了解的内容。
Radiographics. 2021 Jan-Feb;41(1):78-95. doi: 10.1148/rg.2021200087. Epub 2020 Dec 11.
4
Biomarkers for the Diagnosis of Cholangiocarcinoma: A Systematic Review.用于胆管癌诊断的生物标志物：系统评价。
Am J Trop Med Hyg. 2018 Jun;98(6):1788-1797. doi: 10.4269/ajtmh.17-0879. Epub 2018 Apr 5.
5
Biliary Tract Cancer: Epidemiology, Radiotherapy, and Molecular Profiling.胆道癌：流行病学、放射治疗及分子特征分析
Am Soc Clin Oncol Educ Book. 2016;35:e194-203. doi: 10.1200/EDBK_160831.
6
Aspirin use and the risk of cholangiocarcinoma.阿司匹林的使用与胆管癌风险
Hepatology. 2016 Sep;64(3):785-96. doi: 10.1002/hep.28529. Epub 2016 Apr 26.
7
Percutaneous transhepatic cholecystoduodenal stent for empyema of the gallbladder.经皮经肝胆总管十二指肠支架置入术治疗胆囊积脓
Br J Radiol. 2009 Jun;82(978):e108-10. doi: 10.1259/bjr/23124841.
8
Endoscopic drainage of empyema of the gallbladder through a concurrent cholecystoduodenal fistula.
Asian J Surg. 2006 Jan;29(1):55-7. doi: 10.1016/s1015-9584(09)60298-0.
9
Intrahepatic cholangiocarcinoma: macroscopic type and stage classification.肝内胆管癌：大体类型及分期分类
J Hepatobiliary Pancreat Surg. 2003;10(4):288-91. doi: 10.1007/s00534-002-0732-8.
10
Endoscopic transpapillary gallbladder drainage for closure of calculous gallbladder perforation and cholecystoduodenal fistula.
Gastrointest Endosc. 2002 Nov;56(5):753-5. doi: 10.1067/mge.2002.129217.