Walley V M, Turnbull D I
Hum Pathol. 1985 May;16(5):525-8. doi: 10.1016/s0046-8177(85)80094-0.
A case in which unusually large deposits of Tamm-Horsfall protein were identified in perinephric adipose tissue is presented. The deposition around the kidney in this case was most likely due to calyceal rupture, secondary to distal ureteric obstruction. The peculiar gross and microscopic appearance of these deposits, their intense staining with the periodic acid--Schiff technique, and their association microscopically with epithelial fragments raised the possibility of infiltration by mucin-producing adenocarcinoma. The localization of Tamm-Horsfall protein in the deposits by the immunoperoxidase technique helped to confirm their true nature.
本文报道了一例在肾周脂肪组织中发现大量Tamm-Horsfall蛋白沉积的病例。该病例中肾脏周围的沉积物很可能是由于远端输尿管梗阻继发肾盏破裂所致。这些沉积物独特的大体和显微镜下表现、过碘酸-希夫技术染色强烈以及显微镜下与上皮碎片的关联，提示可能是黏液腺癌浸润。免疫过氧化物酶技术对沉积物中Tamm-Horsfall蛋白的定位有助于证实其真实性质。
