Devouassoux-Shisheboran M, Bouvier R, Roux M G, Marechal J M, Vauzelle J L
Service d'Anatomie et de Cytologie Pathologiques, Hôpital Edourad Herriot, Lyon.
Ann Pathol. 1994;14(1):41-4.
Three cases of unusual deposits of Tamm-Horsfall protein in peripelvic and perirenal fat tissue are reported. A renal tubular rupture leads to the deposition of this protein. In the first case, the association of the deposits with epithelial structures, raised the possibility of a bladder carcinoma infiltration. These deposits simulated on the X-ray examination, a pelvis neoplasm in our second patient and a tuberculosis in the third case. However the particular microscopic appearance of Tamm-Horsfall protein, its intense staining with the periodic-acid-Schiff, and its positivity with a specific antibody led to the diagnosis.
报告了3例在肾盂周围和肾周脂肪组织中出现异常Tamm-Horsfall蛋白沉积的病例。肾小管破裂导致该蛋白沉积。在第一例中，沉积物与上皮结构相关，增加了膀胱癌浸润的可能性。在X线检查中，这些沉积物在我们的第二例患者中模拟为盆腔肿瘤，在第三例中模拟为结核病。然而，Tamm-Horsfall蛋白独特的微观外观、其对过碘酸-希夫染色的强烈反应以及对特异性抗体的阳性反应导致了诊断。
