Germani Y, Montaville B, Fauran C, Brethes B
J Clin Microbiol. 1985 Apr;21(4):630-3. doi: 10.1128/jcm.21.4.630-633.1985.
We have studied the incidence of enterotoxigenic Escherichia coli (ETEC) strains isolated from infants with and without diarrheal diseases in Vanuatu, South Pacific. Over a period of 5 months we have isolated enterotoxigenic E. coli strains from 29 (26.6%) of 109 children with acute diarrhea and from 13 (21.6%) of 60 children of the control group. In the group with diarrhea, 7 (6.4%) strains released heat-labile toxin, 7 (6.4%) released heat-stable toxin, and 15 (13.7%) produced both heat-labile and heat-stable toxin. In the control group, only one strain (1.6%) produced heat-stable toxin, 12 (20%) produced heat-labile toxin, and none produced both. Association of strains releasing heat-stable toxin or both heat-labile and heat-stable toxin with diarrhea was highly significant as shown by statistical analysis. The O serogroups and colonization factors CFA/I and CFA/II are presented.
我们研究了从南太平洋瓦努阿图患腹泻病和未患腹泻病的婴儿中分离出的产肠毒素大肠杆菌（ETEC）菌株的发生率。在5个月的时间里，我们从109名急性腹泻儿童中的29名（26.6%）以及对照组60名儿童中的13名（21.6%）分离出产肠毒素大肠杆菌菌株。腹泻组中，7株（6.4%）释放不耐热毒素，7株（6.4%）释放耐热毒素，15株（13.7%）同时产生不耐热和耐热毒素。对照组中，仅1株（1.6%）产生耐热毒素，12株（20%）产生不耐热毒素，无菌株同时产生两种毒素。统计分析表明，释放耐热毒素或同时释放不耐热和耐热毒素的菌株与腹泻的关联极为显著。文中列出了O血清群以及定居因子CFA/I和CFA/II。
