Ray Logan C, Payne Daniel C, Rounds Joshua, Trevejo Rosalie T, Wilson Elisha, Burzlaff Kari, Garman Katie N, Lathrop Sarah, Rissman Tamara, Wymore Katie, Wozny Sophia, Wilson Siri, Francois Watkins Louise K, Bruce Beau B, Weller Daniel L
Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Minnesota Department of Health, St. Paul, Minnesota, USA.
Open Forum Infect Dis. 2024 Apr 9;11(6):ofae199. doi: 10.1093/ofid/ofae199. eCollection 2024 Jun.
In the US, yersinosis was understood to predominantly occur in winter and among Black or African American infants and Asian children. Increased use of culture-independent diagnostic tests (CIDTs) has led to marked increases in yersinosis diagnoses.
We describe differences in the epidemiology of yersiniosis diagnosed by CIDT versus culture in 10 US sites, and identify determinants of health associated with diagnostic method.
Annual reported incidence increased from 0.3/100 000 in 2010 to 1.3/100 000 in 2021, particularly among adults ≥18 years, regardless of race and ethnicity, and during summer months. The proportion of CIDT-diagnosed infections increased from 3% in 2012 to 89% in 2021. An ill person's demographic characteristics and location of residence had a significant impact on their odds of being diagnosed by CIDT.
Improved detection due to increased CIDT use has altered our understanding of yersinosis epidemiology, however differential access to CIDTs may still affect our understanding of yersinosis.
在美国，人们认为耶尔森菌病主要发生在冬季，且多见于黑人或非裔美国婴儿以及亚裔儿童中。非培养诊断检测（CIDTs）使用的增加导致耶尔森菌病诊断显著增多。
我们描述了美国10个地点通过CIDT诊断的耶尔森菌病与通过培养诊断的耶尔森菌病在流行病学上的差异，并确定与诊断方法相关的健康决定因素。
年度报告发病率从2010年的0.3/10万增至2021年的1.3/10万，尤其是在≥18岁的成年人中，无论其种族和族裔如何，且在夏季月份发病率更高。通过CIDT诊断的感染比例从2012年的3%增至2021年的89%。患者的人口统计学特征和居住地点对其通过CIDT诊断的几率有显著影响。
由于CIDT使用增加而带来的检测改善改变了我们对耶尔森菌病流行病学的认识，然而获得CIDT检测的差异可能仍会影响我们对耶尔森菌病的认识。
