Adekunle Olajide A, Schommer Jon C, Wang Yun S, Yunusa Ismaeel, Fleming Marc L, Seoane-Vazquez Enrique, Brown Lawrence M
Department of Pharmaceutical Economics and Policy Chapman, University School of Pharmacy, 9401 Jeronimo Road, Irvine, CA 92618-1908, USA.
Department of Pharmaceutical Care & Health Systems, University of Minnesota 7-155 Weaver-Densford Hall, Minneapolis, MN 55455, USA.
Explor Res Clin Soc Pharm. 2024 May 25;14:100457. doi: 10.1016/j.rcsop.2024.100457. eCollection 2024 Jun.
One factor for the poor health outcomes among adult people with metabolic syndrome (MetS) is poor utilization of disease management resources, which may be attributable to prior experience with pharmacists (PEwP) and perceptions of disease management resource utilization (PMU). Therefore, understanding patients' experience could be critical to improving their perceptions and promoting health outcomes.
The study explored the influence of PEwP and PMU on the health-related quality of life (HRQoL) of people with MetS.
Data on perceptions of healthcare, medication, and pharmacy services utilization, PEwP, and HRQoL were collected using validated tools via an electronic survey. Chi-square and ordinal regression tests were used to predict the association between PMU, PEwP, and HRQoL. Also, mediation analysis through Haye's model 4 explored the direct and indirect relationship of PMU and PEwP on HRQoL.
A total of 706 completed surveys were collected and used for analyses. On average, respondents reported three comorbidities. Of the respondents, 72.0% had good PEwP, while 32.6% had good PMU. Comparatively, 38.4% of those with good PEwP had good PMU, compared to 17.3% of those with poor PEwP. Also, 47.0% of those with good PMU had good HRQoL compared to 35.3% with poor PMU. The odds of having fair or good PMU were nearly triple (OR = 2.97, p < 0.001) among those with good PEwP compared to those with poor PEwP. Also, respondents with good PMU had 58% (OR = 1.58, p = 0.008) higher odds of having fair or good HRQoL. Analysis through bootstrap indicated a significant relationship (BootCI = -0.072, -0.022) between PEwP and HRQoL via respondents' PMU.
MetS individuals with good experience and PMU were more likely to have good HRQoL. Prior experience with pharmacists influenced PMU and indirectly impacted HRQoL. Therefore, pharmacists must consider patients' experience and management utilization perceptions to promote health outcome among people with MetS, while implementing interventions.
代谢综合征（MetS）成年患者健康结局不佳的一个因素是疾病管理资源利用不足，这可能归因于先前与药剂师的接触经历（PEwP）以及对疾病管理资源利用的认知（PMU）。因此，了解患者的经历对于改善他们的认知并促进健康结局可能至关重要。
本研究探讨PEwP和PMU对MetS患者健康相关生活质量（HRQoL）的影响。
通过电子调查，使用经过验证的工具收集有关医疗保健、药物和药房服务利用的认知、PEwP以及HRQoL的数据。使用卡方检验和有序回归检验来预测PMU、PEwP和HRQoL之间的关联。此外，通过海耶斯模型4进行中介分析，探讨PMU和PEwP对HRQoL的直接和间接关系。
共收集到706份完整的调查问卷并用于分析。受访者平均报告有三种合并症。在受访者中，72.0%的人有良好的PEwP，而32.6%的人有良好的PMU。相比之下，PEwP良好的受访者中有38.4%的人PMU良好，而PEwP较差的受访者中这一比例为17.3%。此外,PMU良好的受访者中有47.0%的人HRQoL良好，而PMU较差的受访者中这一比例为35.3%。与PEwP较差的受访者相比，PEwP良好的受访者拥有中等或良好PMU的几率几乎是其三倍（OR = 2.97，p < 0.001）。此外，PMU良好的受访者拥有中等或良好HRQoL的几率高出58%（OR = 1.58，p = 0.008）。通过自抽样法分析表明PEwP与HRQoL之间通过受访者的PMU存在显著关系（BootCI = -0.072，-0.022）。
具有良好经历和PMU的MetS患者更有可能拥有良好的HRQoL。先前与药剂师的接触经历影响了PMU并间接影响了HRQoL。因此，药剂师在实施干预措施时，必须考虑患者的经历和对管理利用的认知，以促进MetS患者的健康结局。
