Department of Materials Science, Institute of Pure and Applied Sciences, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8573, Japan.
Adv Sci (Weinh). 2024 Aug;11(30):e2401947. doi: 10.1002/advs.202401947. Epub 2024 Jun 13.
Perspiration plays a pivotal role not only in thermoregulation but also in reflecting the body's internal state and its response to external stimuli. The up-to-date skin-based wearable platforms have facilitated the monitoring and simultaneous analysis of sweat, offering valuable physiological insights. Unlike conventional passive sweating, dynamic normal perspiration, which occurs during various activities and rest periods, necessitates a more reliable method of collection to accurately capture its real-time fluctuations. An innovative microfluidic patch incorporating a hierarchical superhydrophilic biosponge, poise to significantly improve the efficiency capture of dynamic sweat is introduced. The seamlessly integrated biosponge microchannel showcases exceptional absorption capabilities, efficiently capturing non-sensitive sweat exuding from the skin surface, mitigating sample loss and minimizing sweat volatilization. Furthermore, the incorporation of sweat-rate sensors alongside a suite of functional electrochemical sensors endows the patch of uninterrupted monitoring and analysis of dynamic sweat during various activities, stress events, high-energy intake, and other scenarios.
汗水不仅在体温调节中起着关键作用，还能反映身体的内部状态及其对外部刺激的反应。最新的基于皮肤的可穿戴平台促进了汗液的监测和同时分析，提供了有价值的生理见解。与传统的被动出汗不同，动态正常出汗发生在各种活动和休息期间，需要更可靠的收集方法来准确捕捉其实时波动。引入了一种创新的微流控贴片，其中包含分层超亲水生物海绵，有望显著提高动态汗水的采集效率。无缝集成的生物海绵微通道展示了出色的吸收能力，能够有效地捕获从皮肤表面渗出的非敏感汗水，减少样品损失并最小化汗水挥发。此外，汗液速率传感器的加入以及一系列功能电化学传感器的组合，使贴片能够在各种活动、应激事件、高能量摄入和其他情况下对动态汗液进行不间断的监测和分析。
