School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Biosens Bioelectron. 2024 Sep 15;260:116430. doi: 10.1016/j.bios.2024.116430. Epub 2024 May 24.
Sweat contains abundant physiological and metabolic data to evaluate an individual's physical health. Since the non-exercise sweat secretion rate is low, with an average value of 1-10 μl h cm, sweat is generally collected during exercise for existing wearable sweat sensors. To expand their applications to include daily scenarios, these sensors developed for sports and fitness are challenged by the difficulty of collecting trace amounts of sweat. This study proposes a wearable patch inspired by the hierarchical structure of Sarracenia trichomes, allowing for the spontaneous and fast collection of a small amount of secreted sweat. The patch contains microfluidic channels featuring a 20 μm-wide rib structure, fully utilizing the capillary force, thereby eliminating the issue of sweat hysteresis. Furthermore, with only 0.5 μl of the sweat secreted at the collection site, it can converge on the detection medium located within the center reservoir. Volunteer verification demonstrated a twofold increase in sweat collection efficiency compared to traditional wearable patches. This patch serves as an efficient sweat-collection configuration, promising potential for diverse in situ sweat colorimetric analyses.
汗液中含有丰富的生理和代谢数据，可以评估个体的身体健康状况。由于非运动状态下的汗液分泌率较低，平均为 1-10 μl h cm，因此现有的可穿戴汗液传感器通常在运动时收集汗液。为了将这些传感器的应用扩展到日常场景，为运动和健身开发的传感器在收集微量汗液方面面临挑战。本研究提出了一种受猪笼草毛状体分层结构启发的可穿戴贴片，能够自发快速地收集少量分泌的汗液。该贴片包含微流道，具有 20 μm 宽的肋结构，充分利用毛细作用力，从而消除了汗液滞后的问题。此外，只需在收集点分泌 0.5 μl 的汗液，就可以汇集到位于中央储液器内的检测介质中。志愿者验证表明，与传统的可穿戴贴片相比，该贴片的汗液收集效率提高了两倍。这种贴片是一种高效的汗液收集配置，有望实现各种原位汗液比色分析。
