饮食进餐习惯与冠状动脉狭窄及心脏代谢危险因素之间的关联。
The association between dietary meal intake habits and coronary artery stenosis and cardio-metabolic risk factors.
作者信息
Taftian Marzieh, Sasanfar Bahareh, Sarebanhassanabadi Mohammadtaghi, Seyedhosseini Seyedmostafa, Khayyatzadeh Sayyed Saeid, Madadizadeh Farzan, Motallaei Maryam, Beigrezaei Sara, Golvardi-Yazdi Faezeh, Mirjalili Fatemeh, Salehi-Abargouei Amin
机构信息
Research Center for Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
出版信息
BMC Nutr. 2024 Jun 14;10(1):86. doi: 10.1186/s40795-024-00895-1.
BACKGROUND AND OBJECTIVE
We are not aware of studies examining the association between dietary meal intake habits (DMIH) and severity of coronary artery stenosis (CAS). This study was conducted to investigate the relationship between DMIH and the severity of CAS as well as cardiometabolic risk factors in adults undergoing coronary angiography.
METHODS
This cross-sectional study was done on 720 patients undergoing coronary angiography (aged 35-75 years) who were admitted to Afshar Hospital, a referral hospital for cardiovascular diseases in Yazd, Iran. Data on DMIH were gathered by interview. Blood samples were taken for biochemical analysis. Blood pressure, anthropometric indices, and body composition were also evaluated. The relationship between DMIH and the severity of CAS [examined by angiography based on Gensini Score (GS) and Syntax Score (SS)] and cardiometabolic risk factors were assessed using logistic regression and the analysis of covariance (ANCOVA), respectively, in crude and multivariable adjusted models.
RESULTS
After adjustment for all possible confounding variables, the study revealed that people who ate 3 meals/day had a lower risk of severe CAS compared to people who ate 2 or fewer meals (OR = 0.48, 95% CI: 0.26, 0.88, P-trend = 0.02). There was an inverse association between the number of snacks /day and the severity of CAS (OR = 0.43, 95% CI: 0.22, 0.87, P-trend = 0.02). There was also an inverse relationship between breakfast frequency/week and the severity of CAS based on both GS and SS (P < 0.05). Breakfast consumption, meal frequency, lunch consumption, snack frequency, and more food consumption on holidays were also associated with different cardiometabolic markers and anthropometric measures (P < 0.05).
CONCLUSION
According to the results of the present study, meal frequency and breakfast consumption might be inversely associated with CAS and cardiometabolic risk factors.
背景与目的
我们尚未发现有研究探讨饮食进餐习惯（DMIH）与冠状动脉狭窄（CAS）严重程度之间的关联。本研究旨在调查接受冠状动脉造影的成年人中DMIH与CAS严重程度以及心脏代谢危险因素之间的关系。
方法
本横断面研究对720例接受冠状动脉造影的患者（年龄35 - 75岁）进行，这些患者被收治于伊朗亚兹德的心血管疾病转诊医院阿夫沙尔医院。通过访谈收集DMIH数据。采集血样进行生化分析。还评估了血压、人体测量指标和身体成分。分别在粗模型和多变量调整模型中，使用逻辑回归和协方差分析（ANCOVA）评估DMIH与CAS严重程度[通过基于Gensini评分（GS）和Syntax评分（SS）的血管造影检查]以及心脏代谢危险因素之间的关系。
结果
在对所有可能的混杂变量进行调整后，研究表明，与每天吃两餐或更少餐的人相比，每天吃三餐的人发生严重CAS的风险更低（OR = 0.48，95%CI：0.26，0.88，P趋势 = 0.02）。每天吃零食的次数与CAS严重程度呈负相关（OR = 0.43，95%CI：0.22，0.87，P趋势 = 0.02）。基于GS和SS，每周吃早餐的频率与CAS严重程度也呈负相关（P < 0.05）。早餐摄入量、进餐频率、午餐摄入量、零食频率以及节假日更多的食物摄入量也与不同的心脏代谢指标和人体测量指标相关（P < 0.05）。
结论
根据本研究结果，进餐频率和早餐摄入量可能与CAS及心脏代谢危险因素呈负相关。
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