Hussey Louise Jane, Kontopantelis Evan, Mok Pearl L H, Ashcroft Darren M, Carr Matthew J, Garg Shruti, Chew-Graham Carolyn A, Kapur Nav, Lovell Karina, Webb Roger T
Division of Psychology and Mental Health, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, UK.
Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, UK.
J Child Psychol Psychiatry. 2025 Jan;66(1):16-29. doi: 10.1111/jcpp.14026. Epub 2024 Jun 15.
The impact of the COVID-19 pandemic on the mental health of children and young people (CYP) has been widely reported. Primary care electronic health records were utilised to examine trends in the diagnosing, recording and treating of these common mental disorders by ethnicity and social deprivation in Greater Manchester, England.
Time-series analyses conducted using Greater Manchester Care Record (GMCR) data examined all diagnosed episodes of anxiety disorders and depression and prescribing of anxiolytics and antidepressants among patients aged 6-24 years. The 41-month observation period was split into three epochs: Pre-pandemic (1/2019-2/2020); Pandemic Phase 1 (3/2020-6/2021); Pandemic Phase 2 (7/2021-5/2022). Rate ratios for all CYP specific to sex, age, ethnicity, and neighbourhood-level Indices of Multiple Deprivation (IMD) quintile were modelled using negative binomial regression.
Depression and anxiety disorder rates were highest in females, CYP aged 19-24, and White and 'Other' ethnic groups. During Pandemic Phase 1, rates for these diagnoses fell in all demographic subgroups and then rose to similar levels as those recorded pre-pandemic. In Pandemic Phase 2, rates in Black and Mixed-ethnicity females rose to a significantly greater degree (by 54% and 62%, respectively) than those in White females. Prescribing rates increased throughout the study period, with significantly greater rises observed in non-White females and males. The temporal trends were mostly homogeneous across deprivation quintiles.
The observed fluctuations in frequency of recorded common mental illness diagnoses likely reflect service accessibility and patients' differential propensities to consult as well as changing levels of distress and psychopathology in the population. However, psychotropic medication prescribing increased throughout the observation period, possibly indicating a sustained decline in mental health among CYP, and also clinicians' responses to problems presented. The comparatively greater increases in frequencies of diagnosis recording and medication prescribing among ethnic minority groups warrants further investigation.
新冠疫情对儿童和青少年心理健康的影响已被广泛报道。利用初级保健电子健康记录来研究在英国大曼彻斯特地区,按种族和社会剥夺程度划分的这些常见精神障碍的诊断、记录和治疗趋势。
使用大曼彻斯特护理记录(GMCR)数据进行时间序列分析,研究6至24岁患者中所有焦虑症和抑郁症的诊断发作以及抗焦虑药和抗抑郁药的处方情况。41个月的观察期分为三个阶段:疫情前(2019年1月 - 2020年2月);疫情第一阶段(2020年3月 - 2021年6月);疫情第二阶段(2021年7月 - 2022年5月)。使用负二项回归对所有儿童和青少年按性别、年龄、种族以及邻里层面的多重剥夺指数(IMD)五分位数进行特定的发病率比建模。
抑郁症和焦虑症发病率在女性、19至24岁的儿童和青少年以及白人和“其他”种族群体中最高。在疫情第一阶段,所有人口亚组的这些诊断发病率均下降,然后回升至与疫情前记录的水平相似。在疫情第二阶段,黑人及混血女性的发病率上升幅度明显更大(分别上升54%和62%),高于白人女性。在整个研究期间,处方率均有所上升,非白人女性和男性的上升幅度明显更大。不同剥夺五分位数的时间趋势大多相似。
观察到的记录在案的常见精神疾病诊断频率波动可能反映了服务可及性、患者不同的咨询倾向以及人群中痛苦和精神病理学水平的变化。然而,在整个观察期内精神otropic药物的处方量增加,这可能表明儿童和青少年的心理健康持续下降,也反映了临床医生对所出现问题的应对。少数族裔群体中诊断记录和药物处方频率相对更大幅度的增加值得进一步研究。