Department of Civil, Environmental, and Architectural Engineering, University of Colorado Boulder, Boulder, CO, 80309-0428, US.
Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, 80523-1601, US.
Curr Allergy Asthma Rep. 2024 Jul;24(7):395-406. doi: 10.1007/s11882-024-01157-7. Epub 2024 Jun 15.
This review investigates occupational inhalation hazards associated with biologically derived airborne particles (bioaerosols) generated in indoor cannabis cultivation and manufacturing facilities.
Indoor cannabis production is growing across the US as are recent reports of respiratory diseases among cannabis workers, including occupational asthma morbidity and mortality. More information is needed to understand how bioaerosol exposure in cannabis facilities impacts worker health and occupational disease risk. Preliminary studies demonstrate a significant fraction of airborne particles in cannabis facilities are comprised of fungal spores, bacteria, and plant material, which may also contain hazardous microbial metabolites and allergens. These bioaerosols may pose pathogenic, allergenic, toxigenic, and pro-inflammatory risks to workers. The absence of multi-level, holistic bioaerosol research in cannabis work environments necessitates further characterization of the potential respiratory hazards and effective risk prevention methods to safeguard occupational health as the cannabis industry continues to expand across the US and beyond.
目的综述：本综述调查了与室内大麻种植和制造设施中产生的生物衍生空气传播颗粒（生物气溶胶）相关的职业吸入危害。
最近发现：随着美国各地大麻产量的增加，以及近期报告称大麻工人出现呼吸道疾病，包括职业性哮喘发病率和死亡率，因此需要更多的信息来了解大麻设施中生物气溶胶暴露如何影响工人健康和职业疾病风险。初步研究表明，大麻设施中相当一部分空气传播颗粒由真菌孢子、细菌和植物材料组成，这些颗粒可能还含有有害的微生物代谢物和过敏原。这些生物气溶胶可能对工人造成致病、致敏、产毒和促炎风险。在大麻工作环境中缺乏多层次、整体的生物气溶胶研究，因此需要进一步对潜在的呼吸道危害进行特征描述，并采取有效的风险预防措施，以保护职业健康，因为大麻产业在美国乃至全球范围内持续扩张。
