Applications of Silver Nanoparticles in Pediatric Dentistry: An Overview.

Nanoscience and nanotechnology are emerging fields involved in the synthesis and application of nanoscale materials and structures. Metallic nanoparticles and metallic oxide are being used extensively in dentistry as they interfere with bacterial metabolism and prevent biofilm formation. AgNPs are a class of zero-dimensional materials with distinctive morphologies. The metallic nanoparticles demonstrate the significant antimicrobial activity by ion release, oxidative stress induction, and non-oxidative mechanisms. Metallic silver has been known for its antimicrobial activity since ancient times. Through the years, silver-containing compounds have been used in various forms to treat several medical conditions. Incorporating silver nanoparticles into dental materials may enhance the mechanical features and antibacterial properties of dental materials. Therefore, an increasing number of dental materials with the inclusion of silver nanoparticles are being developed that improve the overall oral health status of patients. This paper aims to review the literature on specific characteristics of silver nanoparticles and their applications in pediatric dentistry.