Kamble Aishwarya N, Chimata Vamsi K, Katge Farhin A, Nanavati Komal K, Shetty Shilpa K
Department of Pediatric and Preventive Dentistry, Terna Dental College, Navi Mumbai, Maharashtra, India.
Int J Clin Pediatr Dent. 2021 Nov-Dec;14(6):752-756. doi: 10.5005/jp-journals-10005-2076.
To evaluate and compare the effect of potassium iodide (KI) and glutathione (GSH) on tooth discoloration after application of 38% silver diamine fluoride (SDF) in primary molars. Total of 30 primary molars were randomly divided into three groups of 10 each. Teeth were prepared and divided into: Group A-SDF only, Group B-SDF followed immediately by application of KI, and Group C-SDF was mixed with 25 mg of GSH. Final restoration was done using glass ionomer cement. Visual examination and color assessments using spectrophotometer were recorded at three time interval points, that is, day 1, 1 week, and 4 weeks.
Statistical analysis was done using a repeated measures analysis of variances (ANOVA) test. The spectrophotometer results showed that Group A (SDF) exhibited the greatest amount of discoloration at all time intervals, while Group C (SDF + GSH) group was effective in decreasing the discoloration. Whereas, Group B (SDF + KI) significantly reduced the discoloration over the period of time. ( = 0.008).
KI can effectively reduce discoloration after application of 38% SDF. GSH can also be used as an alternative.
This two-step treatment for arresting caries can be a practical and low-cost option in areas with limited access to comprehensive dental care.
Kamble AN, Chimata VK, Katge F A, Comparative Evaluation of Effect of Potassium Iodide and Glutathione on Tooth Discoloration after Application of 38% Silver Diamine Fluoride in Primary Molars: An Study. Int J Clin Pediatr Dent 2021;14(6):752-756.
评估并比较碘化钾（KI）和谷胱甘肽（GSH）对乳牙应用38%氟化银胺（SDF）后牙齿变色的影响。总共30颗乳牙被随机分为三组，每组10颗。对牙齿进行处理并分为：A组——仅使用SDF；B组——先使用SDF，随后立即应用KI；C组——SDF与25毫克GSH混合。最终使用玻璃离子水门汀进行修复。在三个时间点，即第1天、1周和4周，记录视觉检查结果以及使用分光光度计进行的颜色评估。
采用重复测量方差分析（ANOVA）进行统计分析。分光光度计结果显示，A组（SDF）在所有时间间隔内变色程度最大，而C组（SDF + GSH）在减少变色方面有效。然而，B组（SDF + KI）在一段时间内显著减少了变色（P = 0.008）。
KI可有效减少应用38% SDF后的牙齿变色。GSH也可作为一种替代方法。
这种两步法龋齿治疗在获得全面牙科护理机会有限的地区可能是一种实用且低成本的选择。
坎布尔AN、奇马塔VK、卡特格FA，《碘化钾和谷胱甘肽对乳牙应用38%氟化银胺后牙齿变色影响的比较评估：一项研究》。《国际临床儿科牙科学杂志》2021年；14(6):752 - 756。
