系统性红斑狼疮患者感染严重急性呼吸综合征冠状病毒 2 后发生数字缺血性坏死：病例报告。
Digital ischemic necrosis in a patient with systematic lupus erythematosus patient after severe acute respiratory syndrome coronavirus 2 infection: a case report.
机构信息
Department of Vascular Surgery, Beijing Chaoyang Hospital, Capital Medical University, NO.8 Gongti South Road, Beijing, 100020, China.
出版信息
J Med Case Rep. 2024 Jun 19;18(1):295. doi: 10.1186/s13256-024-04567-3.
BACKGROUND
Patients with coronavirus disease 2019 have a high incidence of thrombosis that decreases after recovery. When coronavirus disease 2019 is accompanied by diseases prone to thrombosis, risk of post-infection thrombotic events may increase.
CASE PRESENTATION
We report a case of digital ischemic gangrene in a 24-year-old Chinese female with systemic lupus erythematosus after recovery from coronavirus disease 2019. The pathogenesis was related to clinical characteristics of systemic lupus erythematosus, hypercoagulability caused by coronavirus disease 2019, and second-hit due to viral infection.
CONCLUSION
Patients with autoimmune diseases should remain alert to autoimmune system disorders induced by severe acute respiratory syndrome coronavirus 2 and other viruses. Treatment for these patients should be strictly standardized, and appropriate anticoagulation methods should be selected to prevent thrombosis.
背景
新冠肺炎患者血栓形成的发生率较高，在康复后会降低。当新冠肺炎伴有易发生血栓的疾病时，感染后发生血栓性事件的风险可能会增加。
病例介绍
我们报告了一例 24 岁中国女性系统性红斑狼疮患者在新冠肺炎康复后发生的手指缺血性坏疽。发病机制与系统性红斑狼疮的临床特征、新冠肺炎引起的高凝状态以及病毒感染的二次打击有关。
结论
自身免疫性疾病患者应警惕严重急性呼吸综合征冠状病毒 2 及其他病毒引起的自身免疫系统紊乱。这些患者的治疗应严格规范，并选择适当的抗凝方法预防血栓形成。
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