Park Soo-Yeon, Kim Yo-Han, Kim Sung-Jae, Han Jeong-Hee
Department of Veterinary Pathology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Department of Large Animal Internal Medicine, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Animals (Basel). 2024 May 31;14(11):1652. doi: 10.3390/ani14111652.
This study aimed to investigate effects of long-term probiotic supplementation on gut microbiota and growth performance in health weaned piglets. The non-probiotic group (N-PrB) was fed only a basal diet, while the probiotic group (PrB) was fed a basal diet + probiotic combination (. 1.6 × 10 CFU/g, 2.0 × 10 CFU/g, . 3.0 × 10 CFU/g). The probiotics combination was provided to the PrB, mixing with the basal diet in 5 kg/ton. As a result, the PrB exhibited significantly improved weight gain compared to the N-PrB ( = 0.00991). In the gut microbiome analysis, the PrB exhibited a significant increasing tendency of α-diversity compared to those of the N-PrB ( < 0.01). In the bacterial relative abundance changes in bacteria comprising the gut microbiota, ( = 0.00281) and ( = 0.00687) tended to significantly increase in the PrB, but decreased in the N-PrB. The group exhibited an increasing tendency in both groups, but tended to increase more significantly in the PrB compared to the N-PrB ( = 0.00681). tended to significantly increase in the N-PrB, but decreased in the PrB ( = 0.002779). In this study, significant differences on the gut microbiome were found according to the probiotics supplementation in the weaned piglets and these gut microbiome changes appeared to improve the growth performance.
本研究旨在探讨长期补充益生菌对健康断奶仔猪肠道微生物群和生长性能的影响。非益生菌组（N-PrB）仅饲喂基础日粮，而益生菌组（PrB）饲喂基础日粮+益生菌组合（1.6×10CFU/g、2.0×10CFU/g、3.0×10CFU/g）。将益生菌组合按5kg/吨的比例与基础日粮混合后提供给PrB组。结果显示，与N-PrB组相比，PrB组的体重增加显著改善（P=0.00991）。在肠道微生物组分析中，与N-PrB组相比，PrB组的α多样性呈现出显著增加的趋势（P<0.01）。在构成肠道微生物群的细菌相对丰度变化方面，PrB组中（P=0.00281）和（P=0.00687）的丰度有显著增加的趋势，而在N-PrB组中则下降。两组中的该组均呈现增加趋势，但与N-PrB组相比，PrB组的增加趋势更显著（P=0.00681）。N-PrB组中该菌的丰度有显著增加的趋势，而在PrB组中则下降（P=0.002779）。在本研究中，发现断奶仔猪补充益生菌后肠道微生物组存在显著差异，并且这些肠道微生物组的变化似乎改善了生长性能。
