Department of Social Medicine and Public Health, Medical University of Warsaw, 02-106 Warsaw, Poland.
Nutrients. 2024 May 29;16(11):1674. doi: 10.3390/nu16111674.
Anthocyanins are phenolic compounds occurring in fruits and vegetables. Evidence from pre-clinical studies indicates their role in glucose level regulation, gut microbiota improvement, and inflammation reduction under diabetic conditions. Therefore, incorporating these research advancements into clinical practice would significantly improve the prevention and management of type 2 diabetes. This narrative review provides a concise overview of 18 findings from recent clinical research published over the last 5 years that investigate the therapeutic effects of dietary anthocyanins on diabetes. Anthocyanin supplementation has been shown to have a regulatory effect on fasting blood glucose levels, glycated hemoglobin, and other diabetes-related indicators. Furthermore, increased anthocyanin dosages had more favorable implications for diabetes treatment. This review provides evidence that an anthocyanin-rich diet can improve diabetes outcomes, especially in at-risk groups. Future research should focus on optimal intervention duration, consider multiple clinical biomarkers, and analyze anthocyanin effects among well-controlled versus poorly controlled groups of patients with diabetes.
花色苷是存在于水果和蔬菜中的酚类化合物。临床前研究的证据表明，花色苷在调节葡萄糖水平、改善肠道微生物群和减轻糖尿病患者炎症方面发挥作用。因此，将这些研究进展应用于临床实践将显著改善 2 型糖尿病的预防和管理。本综述简要概述了过去 5 年来发表的 18 项关于饮食花色苷对糖尿病治疗作用的最新临床研究结果。花色苷补充剂对空腹血糖水平、糖化血红蛋白和其他糖尿病相关指标具有调节作用。此外，增加花色苷剂量对糖尿病治疗更为有利。本综述提供的证据表明，富含花色苷的饮食可以改善糖尿病的结局，尤其是在高危人群中。未来的研究应侧重于最佳干预持续时间，考虑多种临床生物标志物，并分析糖尿病患者中血糖控制良好和较差组之间花色苷的作用。
