College of Pharmaceutical Science, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou 310014, China.
Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Sensors (Basel). 2024 May 27;24(11):3457. doi: 10.3390/s24113457.
Red ginseng is widely used in food and pharmaceuticals due to its significant nutritional value. However, during the processing and storage of red ginseng, it is susceptible to grow mold and produce mycotoxins, generating security issues. This study proposes a novel approach using hyperspectral imaging technology and a 1D-convolutional neural network-residual-bidirectional-long short-term memory attention mechanism (1DCNN-ResBiLSTM-Attention) for pixel-level mycotoxin recognition in red ginseng. The "Red Ginseng-Mycotoxin" (R-M) dataset is established, and optimal parameters for 1D-CNN, residual bidirectional long short-term memory (ResBiLSTM), and 1DCNN-ResBiLSTM-Attention models are determined. The models achieved testing accuracies of 98.75%, 99.03%, and 99.17%, respectively. To simulate real detection scenarios with potential interfering impurities during the sampling process, a "Red Ginseng-Mycotoxin-Interfering Impurities" (R-M-I) dataset was created. The testing accuracy of the 1DCNN-ResBiLSTM-Attention model reached 96.39%, and it successfully predicted pixel-wise classification for other unknown samples. This study introduces a novel method for real-time mycotoxin monitoring in traditional Chinese medicine, with important implications for the on-site quality control of herbal materials.
红参由于其显著的营养价值,被广泛应用于食品和医药领域。然而,在红参的加工和储存过程中,它容易滋生霉菌并产生真菌毒素,产生安全问题。本研究提出了一种新的方法,使用高光谱成像技术和一维卷积神经网络-残差双向长短期记忆注意力机制(1DCNN-ResBiLSTM-Attention)进行红参中真菌毒素的像素级识别。建立了“红参-真菌毒素”(R-M)数据集,并确定了 1D-CNN、残差双向长短期记忆(ResBiLSTM)和 1DCNN-ResBiLSTM-Attention 模型的最优参数。这些模型的测试准确率分别达到 98.75%、99.03%和 99.17%。为了模拟采样过程中可能存在的潜在干扰杂质的真实检测场景,创建了“红参-真菌毒素-干扰杂质”(R-M-I)数据集。1DCNN-ResBiLSTM-Attention 模型的测试准确率达到 96.39%,并成功预测了其他未知样本的像素级分类。本研究为中药中实时真菌毒素监测引入了一种新方法,对中药材现场质量控制具有重要意义。