Kleinrok Z, Jagiełło-Wójtowicz E, Sieklucka-Dziuba M
Acta Physiol Pol. 1979 Jul-Aug;30(4):437-44.
Effects of fluorostigmine, toxogonin and atropine on monoamine oxidase activity and the level of biogenic amines in mouse brain. Acta physiol. pol., 1979, 30 (4): 437--444. Fluorostigmine (DFP) given i.p. to mice in doses of 1.2 and 2.45 mg/kg reduced MAO activity in the brain. Given in doses of 0.6 and 1.2 mg/kg it reduced the level of noradrenaline and dopamine as well as 5-hydroxytryptamine in the brain. DFP in such doses had no effect on the brain level of 5-hydroxyindoloacetic acid. Toxogonin (5 mg/kg i.p.) or atropine (5 mg/kg i.p.) given together with DFP reduced or abolished completely the inhibitory effect of DFP.
氟斯的明、解磷定和阿托品对小鼠脑内单胺氧化酶活性及生物胺水平的影响。《波兰生理学报》，1979年，30(4):437 - 444。腹腔注射给予小鼠1.2和2.45毫克/千克剂量的氟斯的明（二异丙基氟磷酸酯）可降低脑内单胺氧化酶活性。给予0.6和1.2毫克/千克剂量时，它可降低脑内去甲肾上腺素、多巴胺以及5 - 羟色胺的水平。此剂量的氟斯的明对脑内5 - 羟吲哚乙酸水平无影响。与氟斯的明一起腹腔注射给予解磷定（5毫克/千克）或阿托品（5毫克/千克）可降低或完全消除氟斯的明的抑制作用。
