Jeun So Eun, Kim Kyung Bin, Lee Bong Eun, Kim Gwang Ha, Lee Moon Won, Joo Dong Chan
Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Department of Pathology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Clin Endosc. 2024 Sep;57(5):683-687. doi: 10.5946/ce.2024.051. Epub 2024 Jun 18.
Esophageal mucoepidermoid carcinoma (EMEC) is a special subtype of esophageal malignancy, accounting for less than 1% of all cases of primary esophageal carcinoma. Pathologically, it consists of a mixture of adenocarcinoma and squamous cell carcinoma with mucin-secreting cells. Special staining for mucicarmine helps to diagnose EMEC. We present a rare case of EMEC successfully treated via endoscopic submucosal dissection (ESD). A 63-year-old man was referred to our tertiary hospital. On esophagogastroduodenoscopy, a 6-mm-sized subtle reddish depressed lesion was identified in the mid-esophagus. Diagnostic ESD was performed with a high suspicion of carcinoma. Histopathologic findings were consistent with EMEC which was confined to the lamina propria without lymphatic invasion. We plan to do a careful follow-up without administering adjuvant chemotherapy or radiotherapy. Due to the small volume of the lesion, establishing a diagnosis was difficult through forceps biopsy alone. However, by using ESD, we could confirm and successfully treat a rare case of early-stage EMEC.
食管黏液表皮样癌（EMEC）是食管恶性肿瘤的一种特殊亚型，占原发性食管癌所有病例的比例不到1%。在病理上，它由腺癌、鳞状细胞癌以及黏液分泌细胞混合组成。黏液卡红特殊染色有助于诊断EMEC。我们报告一例通过内镜黏膜下剥离术（ESD）成功治疗的罕见EMEC病例。一名63岁男性被转诊至我们的三级医院。在食管胃十二指肠镜检查中，在食管中段发现一个6毫米大小的细微红色凹陷性病变。因高度怀疑为癌而进行了诊断性ESD。组织病理学检查结果与局限于固有层且无淋巴浸润的EMEC相符。我们计划进行密切随访，不给予辅助化疗或放疗。由于病变体积小，仅通过钳取活检很难确诊。然而，通过使用ESD，我们能够确诊并成功治疗一例罕见的早期EMEC病例。
