Torres Belén, Sánchez María C, Virto Leire, Llama-Palacios Arancha, Ciudad María J, Collado Luis
Faculty of Medicine Department of Medicine Complutense University Madrid Spain.
Faculty of Medicine GINTRAMIS Research Group (Translational Research Group on Microbiota and Health) Complutense University Madrid Spain.
Obes Sci Pract. 2024 Jun 19;10(3):e759. doi: 10.1002/osp4.759. eCollection 2024 Jun.
The prevalence of excess weight and obesity is increasing in an extremely concerning manner worldwide, with highly diverse therapies for current treatment. This review evaluated the scientific evidence of the past 10 years on the use of probiotics in treating excess weight and obesity in the absence of dieting.
A systematic review was conducted by searching for clinical trials on humans published in English in the PubMed, Scopus and Cochrane Central databases, using the combination of keywords "Overweight", "Probiotics" and "Obesity", and published between 2012 and 2022.
Six published studies met the inclusion criteria. The review showed that, although there is a lack of consensus in the literature, the use of probiotics in the absence of dieting produced a significant reduction in body weight and body mass index in 66.6% of the reviewed studies, a significant reduction in waist circumference in 80.0% of the reviewed studies, and an improvement in total body fat mass and waist circumference.
This review showed evidence of a trend in preventing body weight gain and reducing weight through the use of probiotics in individuals with excess weight or obesity. A combination of various strains of the genera and was the most effective.
全球超重和肥胖的患病率正以极其令人担忧的方式上升,目前的治疗方法多种多样。本综述评估了过去10年关于在不节食的情况下使用益生菌治疗超重和肥胖的科学证据。
通过在PubMed、Scopus和Cochrane Central数据库中搜索以英文发表的关于人类的临床试验进行系统综述,使用关键词“超重”、“益生菌”和“肥胖”的组合,发表时间为2012年至2022年。
六项已发表的研究符合纳入标准。该综述表明,尽管文献中缺乏共识,但在不节食的情况下使用益生菌在66.6%的综述研究中使体重和体重指数显著降低,在80.0%的综述研究中使腰围显著降低,并改善了全身脂肪量和腰围。
本综述表明,有证据显示在超重或肥胖个体中使用益生菌有预防体重增加和减轻体重的趋势。多种属和种的菌株组合最为有效。