金催化喹啉-N-氧化物与烯丙酰胺的区域和立体选择性烯基化反应
Gold-Catalyzed Regio- and Stereoselective Alkenylation of Quinoline -Oxides with Allenamides.
作者信息
Lu Mingduo, Liu Yuanhong
机构信息
State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, People's Republic of China.
出版信息
Org Lett. 2024 Jul 5;26(26):5493-5499. doi: 10.1021/acs.orglett.4c01796. Epub 2024 Jun 21.
A gold-catalyzed cycloaddition/ring opening of allenamides with quinoline -oxides has been developed, which provides C2-alkenylated quinolines with high selectivity in moderate to high yields. It is noted that quinoline -oxides with a C8 or C7 substituent are crucial for this catalytic reaction.
已开发出一种金催化的丙二烯酰胺与喹啉氧化物的环加成/开环反应，该反应能以中等到高的产率、高选择性地提供C2-烯基化喹啉。值得注意的是，具有C8或C7取代基的喹啉氧化物对于该催化反应至关重要。
Zotero 插件