Mahmoud Enas, Elsayed Gehad, Hassan Azza, Ateya Ahmed, El-Sayed Shimaa Abd El-Salam
Biochemistry Department, Animal Health Research Institute, Giza, Egypt.
Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Nat Prod Res. 2024 Jun 22:1-7. doi: 10.1080/14786419.2024.2364366.
Algae, as a biological component of the environment, holds promise for the development of novel cuisines. This study aimed to appreciate the dietary () impact on growth patterns and as an immune stimulant in broilers. -fed chicks at 0.5, 1, and 2 g/kg doses significantly improved hematological indices. Also, gas chromatography of fatty acid profile in broiler breast muscles exhibited greater elevation. Serum total proteins, albumin, and globulin levels significantly increased. ElISA (enzyme-linked immunosorbent assay) revealed elevated immunoglobin M, G, and leptin levels as mirrors for immunological response coordination. Reverse transcription polymerase chain reaction (RT-PCR) exhibited depressed tumour necrosis factor-alpha gene expression (TNF-α) in ilial tissue. Gut's histopathology showed well-developed villi. In conclusion, Spirulina platensis in doses up to 2 g/kg enhances immunity, fatty acid profile, liver function, anti-inflammatory properties, and intestinal absorption of broilers, while doses up to 4 g/kg cause the opposite effect on previous parameters.
藻类作为环境中的生物成分，有望用于开发新型美食。本研究旨在评估其对肉鸡生长模式的饮食影响以及作为免疫刺激剂的作用。以0.5、1和2克/千克剂量喂食的雏鸡显著改善了血液学指标。此外，肉鸡胸肌脂肪酸谱的气相色谱分析显示出更大的升高。血清总蛋白、白蛋白和球蛋白水平显著增加。酶联免疫吸附测定（ELISA）显示免疫球蛋白M、G和瘦素水平升高，作为免疫反应协调的指标。逆转录聚合酶链反应（RT-PCR）显示回肠组织中肿瘤坏死因子-α基因表达（TNF-α）降低。肠道组织病理学显示绒毛发育良好。总之，高达2克/千克剂量的钝顶螺旋藻可增强肉鸡的免疫力、脂肪酸谱、肝功能、抗炎特性和肠道吸收，而高达4克/千克剂量则对先前参数产生相反作用。
