Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, National Soybean Processing Industry Technology Innovation Center, Beijing Technology and Business University, Beijing, China.
College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou, 310015, China.
Arch Microbiol. 2024 Jun 22;206(7):322. doi: 10.1007/s00203-024-04053-w.
Limosilactobacillus reuteri DSM17938 is one of the most pivotal probiotics, whose general beneficial effects on the intestinal microbiota are well recognized. Enhancing their growth and metabolic activity can effectively regulate the equilibrium of intestinal microbiota, leading to improved physical health. A common method to promote the growth of Lactobacillus is the addition of prebiotics. Current research suggests that proteins and their hydrolysates from different sources with potential prebiotic activity can also promote the growth of probiotics. In this study, soybean proteins and peptides were effective in promoting the growth, organic acid secretion, and adhesive properties of Limosilactobacillus reuteri DSM17938 to Caco-2 cells. These results illustrate the feasibility of soybean proteins and peptides as prebiotics, providing theoretical and practical advantages for their application.
罗特氏乳杆菌 DSM17938 是最重要的益生菌之一，其对肠道微生物群的普遍有益作用已得到广泛认可。增强其生长和代谢活性可以有效调节肠道微生物群的平衡，从而改善身体健康。促进乳酸菌生长的常用方法是添加益生元。目前的研究表明，具有潜在益生元活性的不同来源的蛋白质及其水解产物也可以促进益生菌的生长。在这项研究中，大豆蛋白和肽有效地促进了罗特氏乳杆菌 DSM17938 的生长、有机酸分泌和对 Caco-2 细胞的黏附特性。这些结果说明了大豆蛋白和肽作为益生元的可行性，为其应用提供了理论和实际优势。
