Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, National Soybean Processing Industry Technology Innovation Center, School of Food and Health, Beijing Technology and Business University, Beijing 100048, China.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, National Soybean Processing Industry Technology Innovation Center, School of Food and Health, Beijing Technology and Business University, Beijing 100048, China.
Food Chem. 2022 Feb 1;369:130923. doi: 10.1016/j.foodchem.2021.130923. Epub 2021 Aug 21.
Lactic acid bacteria are one of the most pivotal probiotics. Promoting their viability could be an effective method to modulate the balance of intestinal flora, thereby improving human health. The current solution is to take advantage of carbon-sourced prebiotics, while protein and peptides with potential prebiotic functions have not been investigated. Soy proteins and peptides have been proven to enhance the growth and metabolism of Lactobacillus. However, research on the relationship between strains of lactobacilli and the structure of soybean peptides is still limited. In the present study, soybean protein and peptides effectively increased the growth and organic acid secretion of Limosilactobacillus reuteri LR08. Additionally, soybean peptides and fructooligosaccharides showed synergistic effects in modulating Limosilactobacillus reuteri LR08. Fraction 1 acquired from soy peptides using RP-HPLC exhibited the most effectiveness and several novel peptides were identified. These results could theoretically and practically benefit soybean peptide application as a potential prebiotic.
乳酸菌是最重要的益生菌之一。促进其存活能力可能是调节肠道菌群平衡从而改善人类健康的有效方法。目前的解决方案是利用碳源的益生元，而具有潜在益生元功能的蛋白质和肽类尚未得到研究。大豆蛋白和肽已被证明可促进乳酸菌的生长和代谢。然而，关于乳酸菌菌株与大豆肽结构之间关系的研究仍然有限。在本研究中，大豆蛋白和肽有效地增加了鼠李糖乳杆菌 LR08 的生长和有机酸分泌。此外，大豆肽和果寡糖在调节鼠李糖乳杆菌 LR08 方面表现出协同作用。使用 RP-HPLC 从大豆肽中获得的馏分 1 表现出最有效的效果，并鉴定出了几种新的肽。这些结果从理论和实践上都有利于将大豆肽作为潜在的益生元应用。
