Lun Tegan, Palamuthusingam Pranavan, O'Rourke Nicholas
Department of Surgery, Townsville University Hospital, Townsville, 4814, QLD, Australia.
Department of Surgery, Royal Brisbane and Women's Hospital, Brisbane, 4006, QLD, Australia.
J Surg Case Rep. 2024 Jun 21;2024(6):rjae418. doi: 10.1093/jscr/rjae418. eCollection 2024 Jun.
A 76-year-old woman was investigated for epigastric pain on a background of a laparoscopic distal pancreatectomy and splenectomy for pancreatic ductal adenocarcinoma 4 years prior. Imaging revealed an isolated 32 mm fluorodeoxyglucose avid lesion contacting both the anterior abdominal wall and greater curvature of the stomach. Immunohistochemistry and fine needle biopsy confirmed a phenotype consistent with metastatic pancreatic adenocarcinoma. Laparoscopic excision of the mass and partial gastrectomy for clearance of margins was performed. Histopathology demonstrated a poorly differentiated pancreatic ductal adenocarcinoma, and the patient received adjuvant gemcitabine/capecitabine following an uncomplicated postoperative course. This article presents a rare case of isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma, which was successfully treated with surgical resection and adjuvant chemotherapy.
一名76岁女性因上腹部疼痛接受检查,4年前因胰腺导管腺癌接受了腹腔镜远端胰腺切除术和脾切除术。影像学检查发现一个孤立的32毫米氟脱氧葡萄糖摄取增加的病变,与前腹壁和胃大弯均有接触。免疫组织化学和细针活检证实其表型与转移性胰腺腺癌一致。遂行腹腔镜肿物切除术及部分胃切除术以清除切缘。组织病理学显示为低分化胰腺导管腺癌,患者术后恢复顺利,随后接受了吉西他滨/卡培他滨辅助化疗。本文报道了一例罕见的胰腺导管腺癌孤立性腹壁复发病例,经手术切除和辅助化疗成功治疗。