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胰腺导管腺癌孤立性腹壁复发:一例罕见病例报告

Isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma: a rare case report.

作者信息

Lun Tegan, Palamuthusingam Pranavan, O'Rourke Nicholas

机构信息

Department of Surgery, Townsville University Hospital, Townsville, 4814, QLD, Australia.

Department of Surgery, Royal Brisbane and Women's Hospital, Brisbane, 4006, QLD, Australia.

出版信息

J Surg Case Rep. 2024 Jun 21;2024(6):rjae418. doi: 10.1093/jscr/rjae418. eCollection 2024 Jun.

Abstract

A 76-year-old woman was investigated for epigastric pain on a background of a laparoscopic distal pancreatectomy and splenectomy for pancreatic ductal adenocarcinoma 4 years prior. Imaging revealed an isolated 32 mm fluorodeoxyglucose avid lesion contacting both the anterior abdominal wall and greater curvature of the stomach. Immunohistochemistry and fine needle biopsy confirmed a phenotype consistent with metastatic pancreatic adenocarcinoma. Laparoscopic excision of the mass and partial gastrectomy for clearance of margins was performed. Histopathology demonstrated a poorly differentiated pancreatic ductal adenocarcinoma, and the patient received adjuvant gemcitabine/capecitabine following an uncomplicated postoperative course. This article presents a rare case of isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma, which was successfully treated with surgical resection and adjuvant chemotherapy.

摘要

一名76岁女性因上腹部疼痛接受检查,4年前因胰腺导管腺癌接受了腹腔镜远端胰腺切除术和脾切除术。影像学检查发现一个孤立的32毫米氟脱氧葡萄糖摄取增加的病变,与前腹壁和胃大弯均有接触。免疫组织化学和细针活检证实其表型与转移性胰腺腺癌一致。遂行腹腔镜肿物切除术及部分胃切除术以清除切缘。组织病理学显示为低分化胰腺导管腺癌,患者术后恢复顺利,随后接受了吉西他滨/卡培他滨辅助化疗。本文报道了一例罕见的胰腺导管腺癌孤立性腹壁复发病例,经手术切除和辅助化疗成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22de/11190851/e6348a181193/rjae418f1.jpg

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