Hospital Oftalmológico de Brasília, SGAS 607 Avenida L2 Sul, Brasília, Distrito Federal, 70200670, Brazil.
Department of Opthalmology, University of Campinas-UNICAMP, Campinas, Brazil.
Int Ophthalmol. 2024 Jun 24;44(1):263. doi: 10.1007/s10792-024-03193-8.
To evaluate the accuracy of a positive self-reported glaucoma family history.
Cross-sectional study. Each subject was asked if they had a first-degree relative diagnosed with glaucoma. If their answer was affirmative, the relative was invited to attend on ophthalmic evaluation and underwent complementary exams to confirm or exclude the glaucoma diagnosis. Only one relative was included per subject.
We included 204 subjects in the study (102 subjects and their respective relatives). The accuracy of family history of glaucoma was 76.96% of the cases. In the univariable analysis, subjects with college degree had 2.34 [(P = 0.010; 95% confidence interval (CI) 1.18-4.63)], with higher family income 3.72 (P = 0.003; 95% CI 1.57-8.85) and those with health insurance 3.42 (P = 0.001; 95% CI 1.67-6.98) more chances to have a true positive family history for glaucoma. In the multivariable logistic regression analysis, none of the variables presented significant association.
Around 24% of patients may not provide reliable information about family history for glaucoma. When asking about a glaucoma family history, clinicians should consider the real accuracy of this self-reported data.
评估阳性自我报告青光眼家族史的准确性。
横断面研究。每个受试者都被问到是否有一级亲属被诊断为青光眼。如果回答是肯定的，则邀请亲属进行眼科评估，并进行补充检查以确认或排除青光眼诊断。每位受试者仅包括一名亲属。
我们纳入了 204 名研究对象（102 名受试者及其各自的亲属）。青光眼家族史的准确率为 76.96%。在单变量分析中，具有大学学历的受试者有 2.34 倍（P=0.010；95%置信区间（CI）1.18-4.63）、较高家庭收入有 3.72 倍（P=0.003；95%CI 1.57-8.85）和有医疗保险的有 3.42 倍（P=0.001；95%CI 1.67-6.98）更有可能有真正的阳性青光眼家族史。在多变量逻辑回归分析中，没有一个变量显示出显著的相关性。
大约 24%的患者可能无法提供有关青光眼家族史的可靠信息。当询问青光眼家族史时，临床医生应考虑到这种自我报告数据的真实准确性。
