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甲基营养型酵母在现代生物技术背景下的应用

Applications of the Methylotrophic Yeast in the Context of Modern Biotechnology.

作者信息

Moraes Lidia Maria Pepe de, Marques Henrique Fetzner, Reis Viviane Castelo Branco, Coelho Cintia Marques, Leitão Matheus de Castro, Galdino Alexsandro Sobreira, Porto de Souza Thais Paiva, Piva Luiza Cesca, Perez Ana Laura Alfonso, Trichez Débora, de Almeida João Ricardo Moreira, De Marco Janice Lisboa, Torres Fernando Araripe Gonçalves

机构信息

Laboratory of Molecular Biology, Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70910-900, DF, Brazil.

Laboratory of Genetics and Biotechnology, Embresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Agroenergy, Brasília 70770-901, DF, Brazil.

出版信息

J Fungi (Basel). 2024 Jun 6;10(6):411. doi: 10.3390/jof10060411.

DOI:10.3390/jof10060411
PMID:38921397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11205268/
Abstract

(formerly ) is a methylotrophic yeast widely used in laboratories around the world to produce recombinant proteins. Given its advantageous features, it has also gained much interest in the context of modern biotechnology. In this review, we present the utilization of as a platform to produce several products of economic interest such as biopharmaceuticals, renewable chemicals, fuels, biomaterials, and food/feed products. Finally, we present synthetic biology approaches currently used for strain engineering, aiming at the production of new bioproducts.

摘要

(以前)是一种甲基营养型酵母,在世界各地的实验室中广泛用于生产重组蛋白。鉴于其有利特性,它在现代生物技术领域也引起了广泛关注。在本综述中,我们介绍了作为一个平台用于生产多种具有经济价值的产品,如生物制药、可再生化学品、燃料、生物材料以及食品/饲料产品。最后,我们介绍了目前用于菌株工程的合成生物学方法,旨在生产新的生物产品。

需注意,原文中“(formerly )”这里括号内容不完整,不太明确具体所指。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/11205268/19df4d55fca1/jof-10-00411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/11205268/19df4d55fca1/jof-10-00411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a9c/11205268/19df4d55fca1/jof-10-00411-g001.jpg

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