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欧洲老年人心肌梗死与衰弱状态的关联:国家和性别的调节作用

Linking Myocardial Infarction and Frailty Status at Old Age in Europe: Moderation Effects of Country and Gender.

作者信息

Sentandreu-Mañó Trinidad, Torres Zaira, Luján-Arribas Cecilia, Tomás José M, González-Cervantes José Javier, Marques-Sule Elena

机构信息

Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain.

Department of Methodology for the Behavioral Sciences, University of Valencia, 46010 Valencia, Spain.

出版信息

J Cardiovasc Dev Dis. 2024 Jun 8;11(6):176. doi: 10.3390/jcdd11060176.

DOI:10.3390/jcdd11060176
PMID:38921676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11203841/
Abstract

BACKGROUND

Myocardial infarction (MI) is a serious condition affecting a considerable number of individuals, with important clinical consequences. Understanding the associated factors is crucial for effective management and prevention. This study aimed to (1) examine the association between MI and frailty in a sample of older European adults and (2) investigate the moderating effects of country and gender on this association.

METHODS

A cross-sectional survey of 22,356 Europeans aged 60 years and older was conducted. The data come from the sixth wave of the Survey of Health, Ageing and Retirement in Europe. Frailty, MI, gender, and country were studied.

RESULTS

Frailty is strongly associated with MI. Robust older adults are 13.31 times more likely not to have an MI. However, these odds drop to 5.09 if pre-frail and to 2.73 if frail. Gender, but not country, moderates this relationship. There is a strong association between MI and frailty in men, whereas for women, the association is not as strong.

CONCLUSIONS

Frailty is highly associated with MI in European older adults. Country did not moderate the link between frailty and MI but gender does, with the relationship being notably stronger in men. The frailty-MI association remained significant even when controlling for a number of personal conditions and comorbidities.

摘要

背景

心肌梗死(MI)是一种严重疾病,影响着相当多的个体,具有重要的临床后果。了解相关因素对于有效管理和预防至关重要。本研究旨在:(1)在欧洲老年成年人样本中检验心肌梗死与衰弱之间的关联;(2)调查国家和性别对这种关联的调节作用。

方法

对22356名60岁及以上的欧洲人进行了横断面调查。数据来自欧洲健康、老龄化和退休调查的第六波。研究了衰弱、心肌梗死、性别和国家。

结果

衰弱与心肌梗死密切相关。健康的老年人患心肌梗死的可能性低13.31倍。然而,如果处于衰弱前期,这一几率降至5.09倍;如果已衰弱,则降至2.73倍。性别而非国家对这种关系有调节作用。心肌梗死与男性的衰弱密切相关,而与女性的关联则没那么强。

结论

在欧洲老年成年人中,衰弱与心肌梗死高度相关。国家并未调节衰弱与心肌梗死之间的联系,但性别起到了调节作用,这种关系在男性中尤为明显。即使在控制了一些个人状况和合并症后,衰弱与心肌梗死之间的关联仍然显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a47/11203841/6f1e37f4091d/jcdd-11-00176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a47/11203841/1aa707957fa1/jcdd-11-00176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a47/11203841/6f1e37f4091d/jcdd-11-00176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a47/11203841/1aa707957fa1/jcdd-11-00176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a47/11203841/6f1e37f4091d/jcdd-11-00176-g002.jpg

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Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction-A Systematic Review.心肌梗死患者心血管疾病危险因素的性别差异——一项系统综述
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