Department of Medical Laboratory Technology, Poltekes Kemenkes Kendari, Southeast Sulawesi, Indonesia.
Faculty of Medicine, Universitas Halu Oleo, Kendari, Southeast Sulawesi, Indonesia.
J Vector Borne Dis. 2024 Apr 1;61(2):167-175. doi: 10.4103/jvbd.jvbd_38_22. Epub 2024 Jun 6.
The incidence of Dengue Hemorrhagic Fever (DHF) continues to increase over time in the world, including Indonesia. One of the prevention efforts against dengue virus transmission is to avoid vector mosquito bites by the use of repellants. Using repellents can reduce exposure to mosquito bites that may cause infection with the dengue virus. This study aimed to determine the effectiveness of repellent lotion composed of patchouli batik extract (Pogostemon cablin) from Southeast Sulawesi varieties against Aedes aegypti mosquitoes.
The research subjects were Aedes aegypti adult mosquitoes. The research consisted of three stages. The first stage was a phytochemical test (qualitative method), the second stage was the analysis of patchouli essential oil (GC-MS method) and the third stage was a test of the effectiveness of lotions made from patchouli extract in lotion preparations against Aedes aegypti.
The results of the effectiveness test of patchouli leaf repellent (Pogestemon cablin) lotion preparations were as follows: for a concentration of 2.5%, protective power 81.5%; concentration 5%, protection power 83.67%; concentration 7.5%, protection power 88.64 %; the concentration of 10%, protection power 90.44%, and the concentration of 12.5% had protection power 90.89%. Probit analysis and linear regression showed the value of ProbitLc 50 was 6.631.
The results of the effectiveness test of Pogestemon cablin repellent lotion preparations with the most effective concentrations were 10% and 12.5%. The results of ANOVA test indicated there was no difference in the average value of the protection power in patchouli leaves.
登革出血热（DHF）的发病率在全球范围内持续增加，印度尼西亚也不例外。预防登革热病毒传播的方法之一是使用驱虫剂避免被病媒蚊叮咬。使用驱虫剂可以减少感染登革热病毒的风险。本研究旨在确定来自苏拉威西东南部品种的广藿香蜡（Pogostemon cablin）驱虫剂的效力，以对抗埃及伊蚊。
研究对象为埃及伊蚊成蚊。研究分为三个阶段。第一阶段是植物化学测试（定性方法），第二阶段是广藿香精油分析（GC-MS 方法），第三阶段是测试由广藿香提取物制成的乳液制剂对埃及伊蚊的效力。
广藿香油驱蚊剂（Pogostemon cablin）乳液制剂效力测试结果如下：浓度为 2.5%时，保护力为 81.5%；浓度为 5%时，保护力为 83.67%；浓度为 7.5%时，保护力为 88.64%；浓度为 10%时，保护力为 90.44%，浓度为 12.5%时，保护力为 90.89%。Probit 分析和线性回归显示 ProbitLc50 值为 6.631。
广藿香驱虫剂乳液制剂的效力测试结果显示，浓度为 10%和 12.5%时最有效。方差分析检验结果表明，广藿香油的保护力平均值没有差异。
