Microtubule shaft integrity emerges as a crucial determinant of the acetylation pattern.
作者信息
Andreu-Carbó Mireia, Egoldt Cornelia, Aumeier Charlotte
机构信息
School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
出版信息
Cytoskeleton (Hoboken). 2025 Jan;82(1-2):55-57. doi: 10.1002/cm.21887. Epub 2024 Jun 24.
Abstract
摘要
相似文献
1
Microtubule shaft integrity emerges as a crucial determinant of the acetylation pattern.微管轴完整性成为乙酰化模式的关键决定因素。
Cytoskeleton (Hoboken). 2025 Jan;82(1-2):55-57. doi: 10.1002/cm.21887. Epub 2024 Jun 24.
2
Microtubule damage shapes the acetylation gradient.微管损伤形成了乙酰化梯度。
Nat Commun. 2024 Mar 6;15(1):2029. doi: 10.1038/s41467-024-46379-5.
3
Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1.α-微管蛋白乙酰转移酶αTAT1进入微管腔的机制。
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7176-E7184. doi: 10.1073/pnas.1605397113. Epub 2016 Nov 1.
4
Causes and Consequences of Microtubule Acetylation.微管乙酰化的原因与后果。
Curr Biol. 2017 Dec 4;27(23):R1287-R1292. doi: 10.1016/j.cub.2017.10.044.
5
Microtubule Acetylation Is Required for Mechanosensation in Drosophila.微管乙酰化对于果蝇的机械感觉至关重要。
Cell Rep. 2018 Oct 23;25(4):1051-1065.e6. doi: 10.1016/j.celrep.2018.09.075.
6
Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule-kinetochore attachment.动态乙酰化的着丝粒相关蛋白 HEC1 确保微管-着丝粒附着的准确性。
J Biol Chem. 2019 Jan 11;294(2):576-592. doi: 10.1074/jbc.RA118.003844. Epub 2018 Nov 8.
7
Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment.一种对微管动力学和货物招募调节至关重要的新型EB1乙酰化位点的表征。
J Cell Physiol. 2018 Mar;233(3):2581-2589. doi: 10.1002/jcp.26133. Epub 2017 Sep 25.
8
CAMSAP2-mediated noncentrosomal microtubule acetylation drives hepatocellular carcinoma metastasis.CAMSAP2 介导的非中心体微管乙酰化驱动肝癌转移。
Theranostics. 2020 Feb 19;10(8):3749-3766. doi: 10.7150/thno.42596. eCollection 2020.
9
Paxillin/HDAC6 regulates microtubule acetylation to promote directional migration of keratinocytes driven by electric fields.桩蛋白/HDAC6 通过调控微管乙酰化促进电场驱动的角质形成细胞的定向迁移。
Biochim Biophys Acta Mol Cell Res. 2024 Feb;1871(2):119628. doi: 10.1016/j.bbamcr.2023.119628. Epub 2023 Nov 10.
10
Eml1 promotes axonal growth by enhancing αTAT1-mediated microtubule acetylation.Eml1 通过增强 αTAT1 介导的微管乙酰化促进轴突生长。
Biochim Biophys Acta Mol Cell Res. 2024 Oct;1871(7):119770. doi: 10.1016/j.bbamcr.2024.119770. Epub 2024 Jun 17.
本文引用的文献
1
Microtubule damage shapes the acetylation gradient.微管损伤形成了乙酰化梯度。
Nat Commun. 2024 Mar 6;15(1):2029. doi: 10.1038/s41467-024-46379-5.
2
A kinesin-1 variant reveals motor-induced microtubule damage in cells.一种肌球蛋白-1 变体揭示了马达诱导的细胞中微管损伤。
Curr Biol. 2022 Jun 6;32(11):2416-2429.e6. doi: 10.1016/j.cub.2022.04.020. Epub 2022 May 2.
3
Motor usage imprints microtubule stability along the shaft.运动使用沿着轴使微管稳定。
Dev Cell. 2022 Jan 10;57(1):5-18.e8. doi: 10.1016/j.devcel.2021.11.019. Epub 2021 Dec 8.
4
Self-repair protects microtubules from destruction by molecular motors.自我修复可保护微管免受分子马达的破坏。
Nat Mater. 2021 Jun;20(6):883-891. doi: 10.1038/s41563-020-00905-0. Epub 2021 Jan 21.
5
MAP6 is an intraluminal protein that induces neuronal microtubules to coil.MAP6 是一种管腔内的蛋白质，可诱导神经元微管卷曲。
Sci Adv. 2020 Apr 1;6(14):eaaz4344. doi: 10.1126/sciadv.aaz4344. eCollection 2020 Apr.
6
ATAT1-enriched vesicles promote microtubule acetylation via axonal transport.富含 ATAT1 的囊泡通过轴突运输促进微管乙酰化。
Sci Adv. 2019 Dec 18;5(12):eaax2705. doi: 10.1126/sciadv.aax2705. eCollection 2019 Dec.
7
Lattice defects induce microtubule self-renewal.晶格缺陷诱导微管自我更新。
Nat Phys. 2019 Aug;15(8):830-838. doi: 10.1038/s41567-019-0542-4. Epub 2019 Jun 3.
8
Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation.切断酶通过晶格 GTP-微管蛋白掺入来扩增微管阵列。
Science. 2018 Aug 24;361(6404). doi: 10.1126/science.aau1504.
9
Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport.相反取向的微管的区分控制着极化神经元的运输。
Neuron. 2017 Dec 20;96(6):1264-1271.e5. doi: 10.1016/j.neuron.2017.11.018. Epub 2017 Nov 30.
10
Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules.人类组蛋白去乙酰化酶 6 对微管二聚体表现出强烈的偏好，而非组装好的微管。
Sci Rep. 2017 Sep 14;7(1):11547. doi: 10.1038/s41598-017-11739-3.
Zotero 插件