Geene J J
Tijdschr Diergeneeskd. 1985 May 1;110(9):345-55.
Of 107 calves studied, forty-one animals (38 per cent) showed diarrhoea during the first week of life of life; only one of the forty-one calves showing diarrhoea died. E. coli K99+ was isolated from twelve calves. Serological studies showed that the concentrations of IgG1 and IgG2 on the first and second days of life were almost equally high in calves with and those without diarrhoea. The differences were more marked as regards the concentrations of IgA and IgM. The Ig fractions of the colostrum immediately after parturition (t = 0), which was supplied to the calves (later, with and without diarrhoea) did not differ; the concentrations of IgG1 and IgM in the colostrum within 24 hours after parturition were significantly lower in those dams, the calves of which subsequently showed diarrhoea. The above results are discussed in greater detail in the comment.
在研究的107头小牛中，有41头（38%）在出生后第一周出现腹泻；41头腹泻小牛中只有1头死亡。从12头小牛中分离出了大肠杆菌K99+。血清学研究表明，腹泻小牛和未腹泻小牛在出生第一天和第二天的IgG1和IgG2浓度几乎一样高。IgA和IgM的浓度差异更为明显。分娩后立即（t = 0）提供给小牛（后来出现腹泻和未出现腹泻的小牛）的初乳中的免疫球蛋白组分没有差异；在分娩后24小时内，其小牛随后出现腹泻的那些母畜的初乳中IgG1和IgM的浓度显著较低。上述结果将在评论中更详细地讨论。
