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墨西哥有围产期脑损伤风险的早产儿童的智力发育:一项纵向研究。

Intellectual Development in Mexican Preterm Children at Risk of Perinatal Brain Damage: A Longitudinal Study.

作者信息

Torres-González Cynthia, Ricardo-Garcell Josefina, Alvarez-Núñez Daniel, Galindo-Aldana Gilberto

机构信息

Faculty of Administrative, Social, and Engineering Sciences, Universidad Autónoma de Baja California, State Hwy No. 3, Guadalupe Victoria, Mexicali 21720, Baja California, Mexico.

Neurodevelopmental Research Unit "Augusto Fernandez Guardiola", Institute of Neurobiology, Autonomous University of Mexico, Boulevard Juriquilla 3001, La Mesa, Juriquilla 76230, Querétaro, Mexico.

出版信息

Children (Basel). 2024 May 28;11(6):652. doi: 10.3390/children11060652.

DOI:10.3390/children11060652
PMID:38929232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11201988/
Abstract

Preterm birth accounts for about 10% of births worldwide. Studying risk factors for perinatal brain damage is essential, as findings suggest that almost 20% of disabilities are linked to risks in the early stages of development. This research aimed to study longitudinal changes in intelligence from 6 to 8 years of age in a sample of 39 preterm children with a history of risk of brain damage and a control group of 35 children born at term. The Wechsler Intelligence Scale (WISC-IV) was used to measure cognitive ability at six, seven, and eight years old. The results showed that the preterm group obtained significantly lower scores than the control group. The working memory indicator significantly affected the interaction between age and prematurity. We consider it crucial to expand the knowledge we have about the neurocognitive development of premature infants, both in specific cognitive domains and in age ranges, so that the information obtained can help predict the probability of presenting cognitive alterations from early stages. This, therefore, helps in implementing intervention strategies and programs based on scientific evidence, and their design is complemented by clinical experience and empirical and theoretical knowledge of the different professionals involved in infant cognitive intervention.

摘要

早产占全球出生人口的约10%。研究围产期脑损伤的风险因素至关重要,因为研究结果表明,近20%的残疾与发育早期的风险有关。本研究旨在对39名有脑损伤风险史的早产儿童样本以及35名足月出生儿童的对照组,研究其6至8岁时智力的纵向变化。使用韦氏智力量表(WISC-IV)测量6岁、7岁和8岁时的认知能力。结果显示,早产组的得分显著低于对照组。工作记忆指标对年龄和早产之间的相互作用有显著影响。我们认为,扩展我们对早产儿神经认知发育的认识至关重要,无论是在特定认知领域还是在年龄范围方面,以便所获得的信息能够帮助预测早期出现认知改变的可能性。因此,这有助于实施基于科学证据的干预策略和项目,其设计辅以临床经验以及参与婴儿认知干预的不同专业人员的经验和理论知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8358/11201988/1798575fe9a8/children-11-00652-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8358/11201988/1798575fe9a8/children-11-00652-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8358/11201988/1798575fe9a8/children-11-00652-g001.jpg

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本文引用的文献

1
National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis.2020 年全球、区域和国家早产估计数及其 2010 年以来的变化趋势:系统分析。
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极低出生体重儿在学龄早期的脑微观结构和功能连接与认知结果及产后生长的关系。
JAMA Netw Open. 2023 Mar 1;6(3):e230198. doi: 10.1001/jamanetworkopen.2023.0198.
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A systematic review of the biological, social, and environmental determinants of intellectual disability in children and adolescents.对儿童和青少年智力残疾的生物学、社会和环境决定因素的系统评价。
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Development of white matter microstructure and executive functions during childhood and adolescence: a review of diffusion MRI studies.儿童和青少年时期脑白质微观结构和执行功能的发展:弥散磁共振成像研究综述。
Dev Cogn Neurosci. 2021 Oct;51:101008. doi: 10.1016/j.dcn.2021.101008. Epub 2021 Aug 25.
8
The dimensions of white matter injury in preterm neonates.早产儿脑白质损伤的程度。
Semin Perinatol. 2021 Nov;45(7):151469. doi: 10.1016/j.semperi.2021.151469. Epub 2021 Aug 20.
9
Multi-domain cognitive impairments at school age in very preterm-born children compared to term-born peers.与足月出生的同龄人相比,极早产儿在学龄时存在多种认知领域的损伤。
BMC Pediatr. 2021 Apr 13;21(1):169. doi: 10.1186/s12887-021-02641-z.
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Cognitive profiles of extremely preterm children: Full-Scale IQ hides strengths and weaknesses.极早产儿的认知特征:全量表智商掩盖了优势和劣势。
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