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口腔微生物群与使用语音假体患者的功能障碍发展有关吗?

Is Oral Microflora Related to Development of Malfunction in Patients Using Voice Prosthesis?

作者信息

Immordino Angelo, Dispenza Francesco, Sireci Federico, Anzalone Riccardo, Immordino Palmira, Calà Cinzia, Gallina Salvatore, Lorusso Francesco

机构信息

Otorhinolaryngology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90127 Palermo, Italy.

Otorhinolaryngology Section, Department Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, 90127 Palermo, Italy.

出版信息

J Clin Med. 2024 Jun 14;13(12):3492. doi: 10.3390/jcm13123492.

Abstract

: this prospective study investigated the correlation between the oral bacterial microflora and the microflora found in voice prostheses (VPs) among 20 patients who had undergone laryngectomy. The aim was to explore the associations between the microflora's presence and the malfunction of VPs, along with the association between the predominant microorganism and the longevity of VPs. : the research process included gathering medical histories, conducting ENT examinations, replacing VPs, and performing check-ups every four months for a period of 15.5 months. Additionally, microbiological examinations, blood tests, and voice change surveys were conducted. : a correlation between the microflora isolated from VPs and that from oral rinses was demonstrated in a large percentage of patients who experienced a loss of prosthetic functional efficiency. The correlation analysis between the type of microorganism and the lifespan of VPs showed a non-significant Pearson correlation coefficient (r = 0.043, = 0.678). : there is no significant linear correlation between the predominant microorganism and the average lifespan of VPs.

摘要

这项前瞻性研究调查了20例喉切除术后患者口腔细菌微生物群与语音假体(VPs)中发现的微生物群之间的相关性。目的是探讨微生物群的存在与VPs功能故障之间的关联,以及主要微生物与VPs使用寿命之间的关联。研究过程包括收集病史、进行耳鼻喉科检查、更换VPs,并在15.5个月的时间里每四个月进行一次检查。此外,还进行了微生物学检查、血液检查和嗓音变化调查。在大部分假体功能效率丧失的患者中,从VPs分离出的微生物群与口腔冲洗液中的微生物群之间存在相关性。微生物类型与VPs使用寿命之间的相关性分析显示,Pearson相关系数无统计学意义(r = 0.043,P = 0.678)。主要微生物与VPs平均使用寿命之间不存在显著的线性相关性。

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