Bolin S R, McClurkin A W, Coria M F
Am J Vet Res. 1985 Apr;46(4):884-6.
The percentage and absolute numbers of circulating B and T lymphocytes were determined for 10 healthy cattle by labeling mononuclear cells with anti-bovine immunoglobulin or peanut agglutinin. The cattle were then inoculated with a cytopathogenic isolate of bovine viral diarrhea (BVD) virus, and B- and T-lymphocyte populations were again quantitated at given intervals. Seemingly, BVD virus caused a decrease in the absolute numbers of B and T lymphocytes and in the percentage of T lymphocytes. Although these effects lasted through 7 days, all of the cattle recovered from infection and had detectable BVD virus-neutralizing antibodies in their sera 17 days after exposure.
通过用抗牛免疫球蛋白或花生凝集素标记单核细胞，测定了10头健康牛循环B淋巴细胞和T淋巴细胞的百分比及绝对数量。然后给这些牛接种牛病毒性腹泻（BVD）病毒的细胞病变分离株，并在给定的时间间隔再次对B淋巴细胞和T淋巴细胞群体进行定量。似乎BVD病毒导致B淋巴细胞和T淋巴细胞的绝对数量以及T淋巴细胞的百分比下降。尽管这些影响持续了7天，但所有牛都从感染中恢复，并且在接触病毒17天后血清中可检测到BVD病毒中和抗体。
