Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.
PLoS One. 2024 Jun 27;19(6):e0305898. doi: 10.1371/journal.pone.0305898. eCollection 2024.
The HIV program in Newfoundland and Labrador (NL) provides care for all persons living with HIV (PLWH) in NL, yet progress toward UNAIDS 95-95-95 goals for diagnosis, linkage to care and viral suppression has not previously been documented. This analysis describes engagement in HIV care and virologic outcomes for the NL cohort in 2016 and 2019 and compares this data to the Canadian HIV Observational Cohort (CANOC). A retrospective review of the NL clinic included adults aged >18 years and descriptive statistics for demographics, risk factors, and clinical variables were assessed and compared using χ2 test or Fisher's Exact test (categorical) or Wilcoxon Sum Rank test (continuous). Engagement in care and virologic outcomes for the NL cohort were consistently high over the 2016 to 2019 period with > 98% on antiretroviral therapy (ART), and > 96% having a suppressed virus load. Engagement in care and virologic outcomes among PLWH in NL is high and compares favorably to a national cohort.
纽芬兰和拉布拉多（NL）的 HIV 项目为 NL 所有 HIV 感染者（PLWH）提供护理，但在实现艾滋病规划署 95-95-95 目标方面，即在诊断、治疗和病毒抑制方面的进展此前并未得到记录。本分析描述了 2016 年和 2019 年 NL 队列参与 HIV 护理和病毒学结果，并将这些数据与加拿大 HIV 观察队列（CANOC）进行了比较。对 NL 诊所的回顾性审查包括年龄 > 18 岁的成年人，并使用 χ2 检验或 Fisher 确切检验（分类）或 Wilcoxon 总和秩检验（连续）评估和比较了人口统计学、危险因素和临床变量的描述性统计数据。在 2016 年至 2019 年期间，NL 队列参与护理和病毒学结果一直很高，接受抗逆转录病毒治疗（ART）的患者比例> 98%，病毒载量被抑制的患者比例> 96%。NL 地区的 PLWH 参与护理和病毒学结果较高，与全国队列相比表现良好。
