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纳米颗粒的生殖毒性研究进展:最新综述

Reproductive toxicity perspectives of nanoparticles: an update.

作者信息

Sree B Kavya, Kumar Nitesh, Singh Sanjiv

机构信息

Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotions Industrial Park (EPIP), Industrial Area Hajipur, Vaishali, Hajipur, Bihar 844102, India.

出版信息

Toxicol Res (Camb). 2024 May 31;13(3):tfae077. doi: 10.1093/toxres/tfae077. eCollection 2024 Jun.

DOI:10.1093/toxres/tfae077
PMID:38939724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11200103/
Abstract

INTRODUCTION

The rapid development of nanotechnologies with their widespread prosperities has advanced concerns regarding potential health hazards of the Nanoparticles.

RESULTS

Nanoparticles are currently present in several consumer products, including medications, food, textiles, sports equipment, and electrical components. Despite the advantages of Nanoparticles, their potential toxicity has negative impact on human health, particularly on reproductive health.

CONCLUSIONS

The impact of various NPs on reproductive system function is yet to be determined. Additional research is required to study the potential toxicity of various Nanoparticles on reproductive health. The primary objective of this review is to unravel the toxic effects of different Nanoparticles on the human reproductive functions and recent investigations on the reproductive toxicity of Nanoparticles both in vitro and in vivo.

摘要

引言

纳米技术的迅速发展及其广泛应用引发了人们对纳米颗粒潜在健康危害的关注。

结果

纳米颗粒目前存在于多种消费品中,包括药物、食品、纺织品、运动器材和电子元件。尽管纳米颗粒具有诸多优势,但其潜在毒性对人类健康,尤其是生殖健康产生负面影响。

结论

各种纳米颗粒对生殖系统功能的影响尚待确定。需要进一步研究各种纳米颗粒对生殖健康的潜在毒性。本综述的主要目的是揭示不同纳米颗粒对人类生殖功能的毒性作用,以及近期关于纳米颗粒体内外生殖毒性的研究。

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