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利用临床人眼像差获取统计最优参数用于高精度像差测量。

Statistical optimal parameters obtained by using clinical human ocular aberrations for high-precision aberration measurement.

作者信息

Yue Xian, Yang Yaliang, Chen Shen, Dai Hao

机构信息

Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu, 610209, China.

Key Laboratory of Adaptive Optics, Chinese Academy of Sciences, Chengdu, 610209, China.

出版信息

Int Ophthalmol. 2024 Jun 28;44(1):292. doi: 10.1007/s10792-024-03176-9.

Abstract

PURPOSE

Compared to Shack-Hartmann wavefront sensor (SHWS), the parameters of virtual SHWS (vSHWS) can be easily adjusted to obtain the optimal performance of aberration measurement. Its current optimal parameters are obtained with only a set of statistical aberrations and not statistically significant. Whether the above parameters are consistent with the statistical results of the optimal parameters corresponding to each set of aberrations, and which performance is better if not? The purpose of this study was to answer these questions.

METHODS

The optimal parameters to reconstruct 624 sets of clinical ocular aberrations in the highest accuracy, including the numbers of sub-apertures (NSAs) and the expansion ratios (ERs) of electric field zero-padding, were determined sequentially in this work. By using wavefront-reconstruction accuracy as an evaluation index, the statistical optimal parameter configuration was selected from some possible configurations determined by the optimal NSAs and ERs.

RESULTS

The statistical optimal parameters are consistent for normal and abnormal eyes. They are different from the optimal parameters obtained with a set of statistical aberrations from the same 624 sets of aberrations, and the performance using the former is better than that using the latter. The performance using a fixed set of statistical optimal parameters is even close to that using the respective optimal parameters corresponding to each set of aberrations.

CONCLUSION

The vSHWS configured with a fixed set of statistical optimal parameters can be used for high-precision aberration measurement of both normal and abnormal eyes. The statistical optimal parameters are more suitable for vSHWS than the parameters obtained with a set of statistical aberrations. These conclusions are significant for the designs of vSHWS and also SHWS.

摘要

目的

与夏克-哈特曼波前传感器(SHWS)相比,虚拟夏克-哈特曼波前传感器(vSHWS)的参数可轻松调整以获得像差测量的最佳性能。其当前的最佳参数仅通过一组统计像差获得,且无统计学意义。上述参数是否与每组像差对应的最佳参数统计结果一致,若不一致哪种性能更佳?本研究旨在回答这些问题。

方法

在本研究中,依次确定了以最高精度重建624组临床眼像差的最佳参数,包括子孔径数量(NSAs)和电场零填充的扩展率(ERs)。以波前重建精度作为评估指标,从由最佳NSAs和ERs确定的一些可能配置中选择统计最佳参数配置。

结果

正常眼和异常眼的统计最佳参数一致。它们与从同一624组像差中的一组统计像差获得的最佳参数不同,且使用前者的性能优于使用后者。使用固定的一组统计最佳参数的性能甚至接近使用每组像差各自对应的最佳参数的性能。

结论

配置有固定一组统计最佳参数的vSHWS可用于正常眼和异常眼的高精度像差测量。统计最佳参数比通过一组统计像差获得的参数更适合vSHWS。这些结论对vSHWS以及SHWS的设计具有重要意义。

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