Ingham E, Eady E A, Holland K T, Gowland G
J Med Microbiol. 1985 Aug;20(1):87-95. doi: 10.1099/00222615-20-1-87.
Seven materials used in the manufacture of tampons-four rayon, one modified rayon, one cotton and one carboxy-methyl cellulose (a modified cotton)-were compared for their effects in vitro on the physiology of a strain of Staphylococcus aureus isolated from a patient with Toxic Shock Syndrome. Experiments were performed in broth culture and, with the exception of two rayon samples, all of the materials tested reduced growth rate and cell yield compared with control values. Exocellular acid phosphatase, lipase, proteinase, hyaluronate lyase and haemolysin in culture filtrates were measured and the lethality of filtrates was determined in mice. The tampon materials had different effects on the levels of exocellular products. Cotton and carboxy-methyl cellulose cotton materials reduced the levels of all of the activities tested. The activities of the other enzymes were reduced or increased, depending on which material was present. All materials reduced both haemolytic activity and lethality of the culture filtrates. The in-vitro data suggest an extremely complex interaction between tampon materials and S. aureus.
对用于制造卫生棉条的七种材料（四种人造丝、一种改性人造丝、一种棉花和一种羧甲基纤维素（一种改性棉花））在体外对从一名中毒性休克综合征患者分离出的金黄色葡萄球菌菌株生理的影响进行了比较。实验在肉汤培养中进行，除了两个 rayon 样品外，与对照值相比，所有测试材料均降低了生长速率和细胞产量。测量了培养滤液中的细胞外酸性磷酸酶、脂肪酶、蛋白酶、透明质酸裂解酶和溶血素，并在小鼠中测定了滤液的致死性。卫生棉条材料对细胞外产物水平有不同影响。棉花和羧甲基纤维素棉材料降低了所有测试活性的水平。其他酶的活性则根据存在的材料而降低或增加。所有材料均降低了培养滤液的溶血活性和致死性。体外数据表明卫生棉条材料与金黄色葡萄球菌之间存在极其复杂的相互作用。
