Nagarajan Shwetha B, Ramakrishnan Sanjeevi, Jayaraman Anuradha
NIMS Institute of Allied Medical Science and Technology NIMS University Rajasthan Jaipur India.
Health Care Sci. 2024 Jun 11;3(3):181-202. doi: 10.1002/hcs2.96. eCollection 2024 Jun.
The exploration of newer antibacterial strategies is driven by antibiotic-resistant microbes that cause serious public health issues. In recent years, nanoscale materials have developed as an alternative method to fight infections. Despite the fact that many nanomaterials have been discovered to be harmful, numerous researchers have shown a keen interest in nanoparticles (NPs) made of noble metals like silver, gold and platinum. To make environmentally safe NPs from plants, green chemistry and nanotechnology have been combined to address the issue of toxicity. The study of bimetallic nanoparticles (BNPs) has increased tremendously in the past 10 years. The production of BNPs mediated by natural extracts is straightforward, low cost and environmentally friendly. Due to their low toxicity, safety and biological stability, noble BNPs with silver, gold, platinum and palladium have the potential to be used in biomedical applications. They have a significant impact on human health and are used in medicine and pharmacy due to their biological characteristics, which include catalytic, antioxidant, antibacterial, antidiabetic, anticancer, hepatoprotective and regenerative activity.
对抗生素具有耐药性的微生物引发了严重的公共卫生问题,这推动了新型抗菌策略的探索。近年来,纳米级材料已发展成为一种对抗感染的替代方法。尽管已发现许多纳米材料具有危害性,但众多研究人员对由银、金和铂等贵金属制成的纳米颗粒(NPs)表现出浓厚兴趣。为了利用植物制备对环境安全的纳米颗粒,绿色化学与纳米技术已结合起来以解决毒性问题。在过去十年中,双金属纳米颗粒(BNPs)的研究大幅增加。由天然提取物介导生产BNPs简便、低成本且环保。由于其低毒性、安全性和生物稳定性,含有银、金、铂和钯的贵金属BNPs有潜力用于生物医学应用。它们对人类健康有重大影响,因其具有催化、抗氧化、抗菌、抗糖尿病、抗癌、保肝和再生活性等生物学特性而被用于医学和制药领域。