Department of Chemical Engineering and Energy, Laboratory of Nanotechnology, Quchan University of Technology, Quchan, Iran.
National Nutrition & Food Technology Research Institute, Faculty of Nutrition & Food Technology Shahid Beheshti University of Medical Sciences, Tehran, 1981619573, Iran.
Food Chem Toxicol. 2022 Nov;169:113406. doi: 10.1016/j.fct.2022.113406. Epub 2022 Sep 5.
Nanotechnology is an interdisciplinary study that has been developing worldwide in recent years and has a serious impact on human life. The fact that the nanoparticles of plant origin are clean, non-toxic, and biocompatible has enabled new fields of study. The Hibiscus sabdariffa (H. sabdariffa) plant has been attracted by scientists because of its impact on health and many other areas. The lipid peroxidation inhibiting activity, antioxidant properties, and antimicrobial properties of H. sabdariffa plant with Ag-Pd metal was ditermined. For the total phenolic component, gallic acid was used as the standard and quarcetin was used for the total flavonoid. The lipid peroxidation inhibition activity of Ag-Pd NPs in ethanol extract was found to be very well compared to the positive control (BHA). The lowest and highest concentrations of DPPH radical scavenging activity were 82.178-97.357%, whereas for BHA these values were found to be 84.142-94.142%. The highest concentration of Ag-Pd NPs at 200 μg/mL the DPPH radical quenching activity was higher than BHA. Ag-Pd NPs showed a good antimicrobial activity against certain pathogenic microorganisms such as Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, which are the causative agents of various diseases in humans. The photodegradation activity of Ag-Pd NPs also investigated against Methyl orange dye (MO) under sunlight irradiation for 120 min and was found to be as 67.88.
纳米技术是近年来在全球范围内发展起来的一门跨学科研究,对人类生活产生了深远的影响。植物来源的纳米颗粒具有清洁、无毒、生物相容性好等特点,为新的研究领域开辟了道路。由于其对健康和许多其他领域的影响,科学家们对洛神花(Hibiscus sabdariffa)产生了兴趣。研究了具有 Ag-Pd 金属的洛神花植物的脂质过氧化抑制活性、抗氧化性能和抗菌性能。对于总酚成分,使用没食子酸作为标准,槲皮素作为总黄酮。与阳性对照(BHA)相比,Ag-Pd NPs 在乙醇提取物中的脂质过氧化抑制活性非常好。DPPH 自由基清除活性的最低和最高浓度分别为 82.178-97.357%,而 BHA 的这些值分别为 84.142-94.142%。Ag-Pd NPs 在 200μg/mL 的最高浓度下对 DPPH 自由基的清除活性高于 BHA。Ag-Pd NPs 对某些致病微生物如枯草芽孢杆菌、粪肠球菌、大肠杆菌、铜绿假单胞菌、白色念珠菌表现出良好的抗菌活性,这些微生物是人类各种疾病的病原体。还研究了 Ag-Pd NPs 在阳光照射下对亚甲基橙染料(MO)的光降解活性,在 120 分钟时为 67.88。