Hargreaves M, Costill D L, Katz A, Fink W J
Med Sci Sports Exerc. 1985 Jun;17(3):360-3.
Eight healthy males were studied to compare the effects of preexercise fructose and glucose ingestion on muscle glycogen usage during exercise. Subjects performed three randomly assigned trials, each involving 30 min of cycling exercise at 75% VO2max. Forty-five min prior to commencing each trial, subjects ingested either 50 g of glucose (G), 50 g of fructose (F), or sweet placebo (C). No differences in VO2 or respiratory exchange ratio were observed between the trials. Blood glucose was elevated (P less than 0.05) as a result of the glucose feeding. With the onset of exercise, blood glucose declined rapidly during G, reaching a nadir of 3.18 +/- 0.15 (SE) mmol X 1(-1) at 20 min of exercise. This value was lower (P less than 0.05) than the corresponding values in F (3.79 +/- 0.20) and C (3.99 +/- 0.18). No differences in exercise blood glucose levels were observed between F and C. Muscle glycogen utilization was greater (P less than 0.05) during G (55.4 +/- 3.3 mmol X kg-1 w.w.) than C (42.8 +/- 4.2). No difference was observed between F (45.6 +/- 4.3) and C. There was a trend (P = 0.07) for muscle glycogen usage to be lower during F than G. These results suggest that the adverse effects of preexercise glucose ingestion are, in general, not observed with either fructose or sweet placebo.
对8名健康男性进行了研究，以比较运动前摄入果糖和葡萄糖对运动期间肌肉糖原利用的影响。受试者进行了三项随机分配的试验，每项试验包括在75%最大摄氧量下进行30分钟的骑自行车运动。在每次试验开始前45分钟，受试者摄入50克葡萄糖（G）、50克果糖（F）或甜味安慰剂（C）。试验之间未观察到最大摄氧量或呼吸交换率的差异。葡萄糖喂养导致血糖升高（P<0.05）。运动开始后，在G试验期间血糖迅速下降，在运动20分钟时达到最低点3.18±0.15（SE）mmol·L⁻¹。该值低于F试验（3.79±0.20）和C试验（3.99±0.18）中的相应值（P<0.05）。F试验和C试验之间未观察到运动期间血糖水平的差异。G试验期间的肌肉糖原利用率（55.4±3.3 mmol·kg⁻¹湿重）高于C试验（42.8±4.2）（P<0.05）。F试验（45.6±4.3）和C试验之间未观察到差异。F试验期间肌肉糖原的使用量有低于G试验的趋势（P=0.07）。这些结果表明，一般来说，运动前摄入葡萄糖的不良影响在摄入果糖或甜味安慰剂时未观察到。
