Ninet J, Fronek A
Microvasc Res. 1985 Jul;30(1):125-32. doi: 10.1016/0026-2862(85)90044-5.
The initial Laser Doppler Flux (LDF) values and skin temperature in the first, third, and fifth finger were evaluated as well as the postocclusion reactive hyperemia (PORH) response to a 4-min suprasystolic compression. The mean values varied from 276.5 to 335.3 mV while the skin temperature ranged from 32.5 to 34.2 degrees. The LDF-monitored PORH response was very reproducible with an average increase of 144.7 +/- 63.6 mV (from an initial LDF value of 327.1 +/- 134 mV). Four different time-related indices were analyzed: t/2recovery = 6.0 +/- 5.5 sec; trecovery (time to reach the initial value) = 16.7 +/- 11.5 sec; tmax (peak of overshoot) = 48.2 +/- 20.6 sec and t/2 overshoot (time to reach 50% of the tmax on the downslope) = 97.4 +/- 31.8 sec. The simultaneously monitored skin temperature changes lagged significantly behind the LDF changes probably due to the large heat capacitance of the tissue. It is expected that the described results obtained from 20 normal subjects will serve as a basis for future clinical studies involving skin perfusion disorders.
评估了第一、第三和第五指的初始激光多普勒血流（LDF）值和皮肤温度，以及对4分钟超收缩期压迫的闭塞后反应性充血（PORH）反应。平均值在276.5至335.3 mV之间，而皮肤温度在32.5至34.2度之间。LDF监测的PORH反应具有很高的可重复性，平均增加144.7±63.6 mV（初始LDF值为327.1±134 mV）。分析了四个不同的时间相关指标：t/2恢复=6.0±5.5秒；trecovery（恢复到初始值的时间）=16.7±11.5秒；tmax（过冲峰值）=48.2±20.6秒；t/2过冲（在下降斜率上达到tmax的50%的时间）=97.4±31.8秒。同时监测的皮肤温度变化明显滞后于LDF变化，这可能是由于组织的大热容量所致。预计从20名正常受试者获得的所述结果将作为未来涉及皮肤灌注障碍的临床研究的基础。
